Anterior Cruciate Ligament (ACL) Rupture

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Review clinical trials related to Anterior Cruciate Ligament (ACL) Rupture. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Synovial Fluid Withdrawal or PRP Injection For Acute ACL Tears and Cytokines

The purpose of this study is to determine what effects the withdrawal of excess knee joint fluid or the injection of a factor from the blood has on swelling after a sudden anterior cruciate ligament (ACL) rupture of the knee.

Participants needed: 99
Trial details
Age: 18-50Biological sex: AllType: InterventionalSponsor: Rush University Medical CenterUpdated: Jun 18, 2026Locations: 1
Eligibility criteria

Age 18 - 50 [+3]

Age <18 or >50 [+4]

Status: Not yet recruiting

Comparison of Video Based Phone App vs. Supervised Preoperative Exercise for ACL Reconstruction

The goal of this clinical trial is to learn if using a phone app for exercises is as effective as working with a physical therapist before anterior cruciate ligament knee surgery. It will also check if exercising before surgery helps patients recover better compared to those who do not follow a specific exercise plan. The main questions it aims to answer are: * Does the phone app help patients improve their knee strength and movement as well as seeing a physical therapist? * Do patients who exercise before surgery have a better recovery after surgery than those who do not? Researchers will compare the phone app group to a physical therapist group and a group with no specific exercise plan to see which method works best. Participants will: * Follow an exercise plan for 4 weeks before their surgery (either using the app, with a therapist, or no specific plan). * Visit the clinic for check-ups before starting the exercises, right before the surgery, and 6 months after the surgery. * Complete simple tests and surveys to measure their knee health.

Participants needed: 66
Trial details
Age: 18-45Biological sex: AllType: InterventionalSponsor: Dr. Lutfi Kirdar Kartal Training and Research HospitalUpdated: Jan 7, 2026Locations: 1
Eligibility criteria

Patients with a diagnosed unilateral Anterior Cruciate Ligament (ACL) rupture [+3]

Patients with multiple ligament injuries (e.g., combined ACL and PCL/MCL injury)... [+4]