Tackling Resistance And HealthCare Economics Through CPE Screening
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorImperial College London
About this trial
The goal of this clinical study is to learn if it is possible to reduce the spread of resistant bacteria called CPEs (Carbapenemase producing Enterobacterales) between patients admitted to hospital.
CPEs can be carried in the gut of people without making them ill. Normally when patients come into hospital, they may undergo a swab test on their bottom to see if CPEs can be grown. This test can take up to 24 hours to produce a result.
The investigators want to use a faster test which takes 2 hours to produce a result, and whether this can make a difference to CPE spread between person to person.
The main questions it aims to answer are:
1. Why do people carry, transmit or get infected with CPE? 2. If a faster test was used to look for CPE, would this be better at reducing patient spread in hospital? 3. Is a faster test also more cost effective?
Participants will:
1. Be tested by both the usual and faster test when they come into hospital by a swab on their bottom 2. Where they test positive for CPE they will be asked to answer some questions about their health
Eligibility criteria
Qualifiers
All adult (18 years or older) medical patients admitted to the acute medical unit during the implementation period who undergo routine rectal CPE testing as per local Trust policy and test positive for CPE colonisation through either the rapid test or culture-based methods.
Disqualifiers
Patient refusal for rectal screening or
Clinical contraindication to rectal swab collection
Trial design
Treatments tested in this trial
- Rapid molecular diagnostic test for CPE identification
Treatment groups
16,000 Participants
are divided into 1 treatment groupSponsors and collaborators
Source ClinicalTrials.gov