In individuals with inflammatory bowel disease (IBD), bowel cancer can develop from abnormal cell changes (dysplasia). Regular colonoscopies are recommended to identify these early changes, which can be difficult to detect because they are often small and subtle. Dye-based imaging has been used to improve detection, but it requires additional preparation and time. Texture and Colour Enhancement Imaging (TXI) is a newer method available in clinical practice that adjusts brightness, colour, and texture on high-definition cameras. This study will compare TXI with dye-based imaging to assess which approach detects precancerous changes more effectively in patients with IBD.
Patients >16 with inflammatory bowel disease undergoing surveillance colonoscopy.
Patients with Crohn's (L2/L3 Montreal classification) with >50% colonic involvement
Patients with ulcerative colitis with Extensive or left sided disease (E3 or E2 Montreal classification) for at least 8 years or a diagnosis of Primary sclerosing cholangitis concomitant with IBD.
Disease duration <8 years unless a diagnosis of PSC
Incomplete colonoscopy
BBPS <6 or <2 in any segment
MES ≥2 or any variable of the SES-CD is ≥2 or any stenosis for >10cm segment (above the rectum)