The purpose of this randomized, double-blind, placebo-controlled crossover study is to evaluate the efficacy of the acute effects of an investigational supplement (Alpha Brain or Alpha Brain 2.0) on improving cognitive performance, vigilance, and subjective mood in healthy adults compared to placebo during a period of acute sleep deprivation under conditions of controlled sleep deprivation.
Healthy males and females aged 20-59
Free of chronic diseases.
Able to read and write in English
Willing to maintain a habitual diet, supplement routine, and avoid other lifestyle changes during the study period
Habitual high caffeine consumers (> 400 mg/day) assessed through caffeine assessment tool (Caffeine Consumption Questionnaire, CCQ)
Unwilling to wear sleep monitor at night
Known diagnosis of any cognitive impairment, cardiovascular, metabolic, endocrine, or renal disease
Has fever, or cold like symptoms