The Analgesic Efficacy of Dexmedetomidine Versus Fentanyl as an Adjuvant to Bupivacaine in Ultrasound Guided Peripheral Nerve Blocks as a Solo Anesthetic Technique in High Risk Patients Undergoing Unilateral Above Knee Amputation .

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorKasr El Aini Hospital

About this trial

The aim of this study is to compare the analgesic efficacy and safety of dexmedetomidine versus fentanyl as adjuvants to bupivacaine in ultrasound-guided combined supra-inguinal fascia iliaca and proximal sciatic nerve blocks used as a solo anesthetic technique in high-risk patients undergoing unilateral above knee amputation.

Eligibility criteria

Qualifiers

- Age ≥18 years

Both sexes

ASA III-IV

Documented cardiac disease (e.g., EF < 40%, NYHA II or higher)

Disqualifiers

Neurological or intellectual disability

Drug abuse

Allergy to study drugs

Pregnancy

Trial design

Treatments tested in this trial

  • Dexmedetomidine
  • Fentanyl (as Citrate)

Treatment groups

64 Participants
are divided into 2 treatment groups

Sponsors and collaborators