Health Trials

Above Knee Amputation

4

Review clinical trials related to Above Knee Amputation. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

The Analgesic Efficacy of Dexmedetomidine Versus Fentanyl as an Adjuvant to Bupivacaine in Ultrasound Guided Peripheral Nerve Blocks as a Solo Anesthetic Technique in High Risk Patients Undergoing Unilateral Above Knee Amputation .

The aim of this study is to compare the analgesic efficacy and safety of dexmedetomidine versus fentanyl as adjuvants to bupivacaine in ultrasound-guided combined supra-inguinal fascia iliaca and proximal sciatic nerve blocks used as a solo anesthetic technique in high-risk patients undergoing unilateral above knee amputation.

Participants needed: 64
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Kasr El Aini HospitalUpdated: Jul 13, 2026Locations: 1
Eligibility criteria

- Age ≥18 years [+5]

Neurological or intellectual disability [+7]

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Status: Not yet recruiting

The Analgesic Efficacy of Dexmedetomidine Versus Fentanyl as an Adjuvant to Bupivacaine in Ultrasound Guided Peripheral Nerve Blocks as a Solo Anesthetic Technique in High Risk Patients Undergoing Unilateral Above Knee Amputation .

The aim of this study is to compare the analgesic efficacy and safety of dexmedetomidine versus fentanyl as adjuvants to bupivacaine in ultrasound-guided combined supra-inguinal fascia iliaca and proximal sciatic nerve blocks used as a solo anesthetic technique in high-risk patients undergoing unilateral above knee amputation.

Participants needed: 64
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Kasr El Aini HospitalUpdated: Jun 10, 2026Locations: 1
Eligibility criteria

- Age ≥18 years [+5]

Neurological or intellectual disability [+7]

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Status: Recruiting

Intrathecal Dexmedetomidine-Fentanyl Combination Versus Fentanyl Alone as Adjuvant to Bupivacaine in Spinal Anesthesia for Above Knee Amputation in Sarcomas of Lower Extremity

The current work evaluated whether the combination of intrathecal dexmedetomidine and fentanyl provides superior postoperative analgesia to fentanyl alone when administered with hyperbaric bupivacaine.

Participants needed: 58
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: National Cancer Institute, EgyptUpdated: Dec 11, 2025Locations: 1
Eligibility criteria

Age from 18 to 60 years. [+5]

Allergy to any of the investigated drugs. [+4]

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Status: Recruiting

Gait Training and Artificial Intelligence

Effect of Using Artificial Intelligence on Gait Training in Above Knee Amputation Patients

Participants needed: 40
Trial details
Age: 16-50Biological sex: AllType: InterventionalSponsor: South Valley UniversityUpdated: Dec 4, 2025Locations: 1
Eligibility criteria

All patients have above-knee amputations. [+3]

Patients have any complications affecting joint ROM. [+2]

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