The Association of Transgelin-2, Metallothionein-2 and Ezrin With Asthma
ConditionAsthma
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age14-75
SponsorShanghai University of Traditional Chinese Medicine
About this trial
Asthma is one of the most common chronic respiratory diseases. Previous study found a series of differentially expressed genes and proteins (transgelin-2, metallothionein-2, ezrin) in asthmatic rat. The aim of the study is to investigate the changes and associations of these gene with asthma in human.
Eligibility criteria
Qualifiers
Males or females, aged 14-75 years;
Patients with a definite diagnosis of bronchial asthma;
The diagnosis of asthma according to the Global Initiative for Asthma (GINA), with positive bronchodilator responsiveness (reversibility) test;
Healthy volunteers without respiratory symptoms such as cough, wheezing, chest tightness or dyspnea;
Disqualifiers
Patients with chronic obstructive pulmonary disease or other airway disease;
Complicated with other severe primary diseases (including hypertension, cancer, hyperthyroidism, bronchiectasia, cardiac insufficiency) and conditions that would prevent participation in the trial or put the participant at risk;
Women who are known to be pregnant or breastfeeding;
Not willing to participate;
Trial design
Treatments tested in this trial
- No intervention
Treatment groups
100 Participants
are divided into 2 treatment groupsSponsors and collaborators
Shanghai University of Traditional Chinese Medicine
Lead sponsor
Xiangya Hospital of Central South University
Collaborator
National Natural Science Foundation of China
Collaborator
Source ClinicalTrials.gov