Health TrialsbyHealthPanel

The Effect of Body Mass Index on Short-term Results of HTO

ConditionsOsteo Arthritis KneeVarus Knee
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40-60
SponsorEgymedicalpedia

About this trial

The knee joint plays a major role in weight transmission of the body in day-to-day activities. The biomechanics of the knee and malalignment in lower limb anatomy are major risk factors for chronic knee pain, leaving Total Knee Arthroplasty (TKA) as the best and most successful option for patients with end-stage osteoarthritis (OA)

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Meet the diagnostic criteria for knee osteoarthritis and only have one knee

No serious underlying medical disease

Conservative treatment is ineffective and there is a willingness for surgery

X-ray shows degeneration limited to the medial joint space (Ahlback grade ≥ grade II)

Disqualifiers

knee osteoarthritis caused by infection, blood-related or autoimmune diseases.

severe obesity (BMI>35 kg/m 2 ) or morbid obesity (obesity caused by diseases such as hypercortisolism and hypothyroidism, BMI≥30 kg/m 2 ).

Trial design

Design model

Single group

Treatments tested in this trial

  • High tibial osteotomy (HTO

    Procedure/Surgery

    To investigate the effect of body mass index (BMI) on the early efficacy of high tibial osteotomy (HTO) in the treatment of varus knee osteoarthritis

Treatment groups

50 Participants
are divided into 1 treatment group
Group A: varus knee osteoarthritis GroupExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Blood Loss (defined as blood loss ≥500 cc)

Assessment of bleeding intraoperative and post operative by measuring Hemoglobin level and Hematocrit level pre and post operation.

Time frame
First 2 hours till 3 days after the operation

Secondary outcomes

1

Knee Joint Function

Evaluated using HSS score, knee range of motion before and after the operation.

Time frame
Two hours after the operation
2

Assessment of Pain

Assessment of Pain by using VAS score for pain status

Time frame
Two hours after the operation

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Egymedicalpedia

Lead sponsor

Al-Azhar University

Collaborator

Source ClinicalTrials.gov
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