The Effects of Age on Muscle Endurance During Resistance Exercise With and Without Blood Flow Restriction

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age19+
SponsorUniversity of British Columbia

About this trial

The purpose of this study is to learn how aging affects muscle endurance during resistance exercise, and how oxygen delivery to the muscles plays a role in these changes. To answer this question, we are comparing how many repetitions of a leg exercise (knee extensions) younger and older adults can do at different exercise intensities. We will also look at how the muscles use oxygen during these exercises.

Participants will take part in 12 different exercise sessions. In each session, they will perform as many knee extensions as possible using different amounts of weight-consisting of 20%, 30%, 40%, 50%, 60% and 70% of the maximum weight they can lift one time. Each weight will be tested both with and without a cuff on the leg that temporarily reduces blood flow to the muscle.

Eligibility criteria

Qualifiers

Able to understand and communicate in English

19-35 years of age

65 years of age or older

All "No" answers on the CSEP Get Active questionnaire or doctors' approval to participate

Disqualifiers

BMI lower than 18 or greater than 32

Current use of cigarettes or other nicotine devices

Any major uncontrolled cardiovascular, muscular, metabolic, and/or neurological disorders

Any medical condition impacting the ability to participate in maximal exercise

Trial design

Treatments tested in this trial

  • Knee extension exercise

Treatment groups

20 Participants
are divided into 2 treatment groups

Sponsors and collaborators