About this trial
Anterior rectal resection has become the primary surgical treatment for rectal cancer. However, studies have reported that up to 80%-90% of patients who undergo anterior rectal resection experience varying degrees of defecation dysfunction after surgery, such as frequent bowel movements, urgent bowel movements, and faecal incontinence, known as low anterior resection syndrome (LARS). This can lead to a decline in quality of life after surgery and even partial loss of social functioning.
Eligibility criteria
Qualifiers
According to the NCCN guidelines for the pathological diagnosis of rectal cancer, the patient has primary rectal adenocarcinoma;
Age ≥ 18 years;
Previously underwent rectal resection with prophylactic ileostomy via laparoscopy, robotics, or open surgery;
Expected to undergo ileostomy reversal surgery within 1-2 months;
Disqualifiers
American Society of Anesthesiologists (ASA) classification III or higher;
Concurrent inflammatory bowel disease, Crohn's disease, or other intestinal diseases;
Mental disorders, long-term use of psychiatric drugs;
Contraindications to enemas.
Trial design
Treatments tested in this trial
- antegrade enema
- retrograde enema