The Efficacy of the KARL STORZ Curved Fetoscope and Straight Fetoscope for Laser Photocoagulation of Placental Anastomoses

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-45
SponsorJimmy Espinoza

About this trial

The purpose of this study is to evaluate the efficacy of KARL STORZ curved fetoscope (11508AAK) and its straight version (11506AAK) for laser photocoagulation of placental anastomoses in patients with an anterior placenta and Twin to Twin Transfusion Syndrome (TTTS).

Eligibility criteria

Qualifiers

pregnancy

The patient fulfills the criteria for laser photocoagulation of placental anastomoses based on the standard of care

fetal diagnosis of twin-to-twin transfusion syndrome

Anterior placenta

Disqualifiers

Contraindication to abdominal surgery, fetoscopic surgery, or general anesthesia

Allergy or previous adverse reaction to a study medication specified in this protocol

The patient does not fulfill the conventional criteria to undergo in-utero surgery, which is specific for each surgery

Preterm labor, preeclampsia, or a uterine anomaly (e.g., large fibroid tumor) that is unavoidable during surgery in the index pregnancy

Trial design

Treatments tested in this trial

  • Curved KARL STORZ fetoscope
  • Conventional Scopes

Treatment groups

160 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Jimmy Espinoza

Lead sponsor

The University of Texas Health Science Center, Houston

Sponsor institution