About this trial
The purpose of this study is to evaluate the efficacy of KARL STORZ curved fetoscope (11508AAK) and its straight version (11506AAK) for laser photocoagulation of placental anastomoses in patients with an anterior placenta and Twin to Twin Transfusion Syndrome (TTTS).
Eligibility criteria
Qualifiers
pregnancy
The patient fulfills the criteria for laser photocoagulation of placental anastomoses based on the standard of care
fetal diagnosis of twin-to-twin transfusion syndrome
Anterior placenta
Disqualifiers
Contraindication to abdominal surgery, fetoscopic surgery, or general anesthesia
Allergy or previous adverse reaction to a study medication specified in this protocol
The patient does not fulfill the conventional criteria to undergo in-utero surgery, which is specific for each surgery
Preterm labor, preeclampsia, or a uterine anomaly (e.g., large fibroid tumor) that is unavoidable during surgery in the index pregnancy
Trial design
Treatments tested in this trial
- Curved KARL STORZ fetoscope
- Conventional Scopes
Treatment groups
Sponsors and collaborators
Jimmy Espinoza
Lead sponsor
The University of Texas Health Science Center, Houston
Sponsor institution