Thermal Ablation Vs Thyroidectomy for Large Benign Thyroid Nodules
ConditionBenign Thyroid Nodules
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorMing-an Yu
About this trial
To compare the safety, efficacy and quality of life between staged thermal ablation and thyroidectomy in the treatment of Large benign thyroid nodules.
Eligibility criteria
Qualifiers
benign thyroid nodules confirmed by surgical pathology in surgery group, and by two separate US-guided fine-needle aspiration (FNA) or core needle biopsy (CNB) in thermal ablation group;
the largest diameter of the nodule ≥4 cm;
the presence of nodule-related symptoms, cosmetic concerns, or psychological stress;
patients treated with surgery, or staged thermal ablation (who explicitly refused surgery);
Disqualifiers
suspicion of malignant nodule on ultrasound findings (e.g., marked hypoechoic, microcalcifications, or ill-defined margins);
comorbidities of other severe diseases;
without complete treatment and/or follow-up information
Trial design
Treatments tested in this trial
- surgery
- staged thermal ablation
Treatment groups
300 Participants
are divided into 2 treatment groupsSponsors and collaborators
Ming-an Yu
Lead sponsor
China-Japan Friendship Hospital
Sponsor institution
Source ClinicalTrials.gov