Clinical trials

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Search and review clinical trials. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Humanistic Continuing Care Via WeChat for Patients Undergoing Thermal Ablation of Papillary Thyroid Carcinoma

The goal of this clinical trial is to test whether human-centered nursing care lowers emotional distress and improves quality of life for people who are awake during thyroid thermal ablation. The procedure uses local anesthesia, so participants remain awake and may feel tense. Human-centered care focuses on emotional support, clear communication, comfort, and follow-up, and it may improve the experience and recovery for patients. The main questions are: Does human-centered nursing care reduce emotional distress levels in patients undergoing thyroid thermal ablation? Does human-centered nursing care improve patient quality of life after thyroid thermal ablation? If there is a comparison group: Researchers will compare human-centered nursing care to usual nursing care to see if human-centered care leads to lower emotional distress and higher quality of life. Participants will: Receive either human-centered nursing care or usual nursing care. Complete questionnaires before, during, and after the procedure to measure emotional distress, quality of life, pain, and satisfaction with care. Have their vital signs and quality of life tracked during and after the procedure. Have their adherence to care plans and any complications monitored. The main outcomes are emotional distress levels and quality of life. Other outcomes include pain and vital signs during the procedure, satisfaction with care, and complication rates. Results may guide better care for people undergoing small, minimally invasive treatments while awake.

Participants needed: 108
Trial details
Age: 16-60Biological sex: AllType: InterventionalSponsor: Ming-an YuUpdated: Dec 24, 2025Locations: 1
Eligibility criteria

Age 16-60 years; scheduled for thyroid thermal ablation [+4]

Serious medical comorbidities or cognitive impairment that precludes participati... [+2]

Status: Recruiting

Health-Related Quality of Life and Emotions in Patients with Thyroid Nodules

The purpose of this observational research is to evaluate and compare the health-related quality of life and emotional well-being of patients with thyroid nodules before and after treatment. This is a data collection study by allowing investigators to access information generated before and after treatment.

Participants needed: 500
Trial details
Age: 18-70Biological sex: AllType: ObservationalSponsor: Ming-an YuUpdated: Sep 24, 2024Locations: 1
Eligibility criteria

Clinical diagnosis of benign thyroid nodules or papillary thyroid carcinoma ; [+2]

serious primary diseases in the liver, kidney, hematopoietic, or endocrine syste... [+1]

Status: Not yet recruiting

Thermal Ablation Vs Thyroidectomy for Large Benign Thyroid Nodules

To compare the safety, efficacy and quality of life between staged thermal ablation and thyroidectomy in the treatment of Large benign thyroid nodules.

Participants needed: 300
Trial details
Age: 18-80Biological sex: AllType: ObservationalSponsor: Ming-an YuUpdated: Sep 23, 2024Locations: 1Duration: 6 Months
Eligibility criteria

benign thyroid nodules confirmed by surgical pathology in surgery group, and by... [+4]

suspicion of malignant nodule on ultrasound findings (e.g., marked hypoechoic, m... [+2]