Time Restricted Eating for WeIght LoSs MainTenance-2
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age25-65
SponsorNYU Langone Health
About this trial
The TWIST 2.0 Study is a 12-month, 2-arm RCT in adults with recent weight loss. We will examine the efficacy of TRE on weight (Aim 1a) and fat mass (Aim 1b) regain, and describe changes in subjective appetite following a mixed-meal tolerance test (Exploratory).
Eligibility criteria
Qualifiers
≥5% non-surgical weight loss in the last 3 mos;
current BMI 20.5-45 mg/kg2;
between the ages 25 to 65 years old;
own a smartphone or willing to use a smartphone if provided for self-monitoring. For in-person screening, eligible participants will provide signed informed consent and have their temporal eating patterns measured.
Disqualifiers
pregnant, trying to get pregnant or breastfeeding;
previous or planned bariatric surgery;
previous or current history of eating disorder;
ongoing participation in another weight-management research study;
Trial design
Treatments tested in this trial
- TRE
- Weight-Loss Maintenance Advice
Treatment groups
110 Participants
are divided into 2 treatment groupsSponsors and collaborators
NYU Langone Health
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Collaborator
Source ClinicalTrials.gov