Timing and Facilitation Effects of Theta-Burst Stimulation in the Reading and Language Networks
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-30
SponsorGeorgia State University
About this trial
The purpose of this study is to understand how transcranial magnetic stimulation affects how quickly, easily, and accurately a person read. Transcranial magnetic stimulation is a technique that uses magnetic fields to briefly affect how well certain brain regions function. The investigators would like to better understand how long the effects of transcranial magnetic stimulation occur in the reading system and at what point the effect is strongest in this system. The main questions it aims to answer are:
1. At what point after stimulation are the greatest effects on behavior seen 2. How excitatory and inhibitory stimulation affect behavior
Researchers will compare stimulation types against a sham condition to see effects on reading and language behavior.
Participants will be asked to
* undergo reading, language, and cognitive testing * receive an MRI * receive TMS stimulation * perform language, reading, and motor tasks
Eligibility criteria
Qualifiers
Subjects must have a minimum of low average intellectual functioning (>=80) on at least one subscale on the Wechsler Abbreviated Scale of Intelligence-2 (WASI-2; Wechsler, 2011) to be included.
Within a normal range of reading skills as >85 on the Test of Word Reading Efficiency - Second Edition (TOWRE-2; Torgesen et al., 2012) and the Woodcock-Johnson IV Tests of Achievement (WJ-IV; Schrank et al., 2014)
Individuals with a documented history of learning disability will not be included. This will be determined via demographics questionnaire.
Subjects must be between the ages of 18 and 30 to be included. This will be determined via demographics questionnaire.
Disqualifiers
None
Trial design
Treatments tested in this trial
- iTBS
- cTBS
- Sham Stimulation
Treatment groups
50 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov