About this trial
While the reduced hemorrhagic risk of radial access for percutaneous coronary intervention compared to femoral access is well-established, its main complication remains radial artery occlusion, which can occur in up to 30% of patients. Anticoagulation is the primary preventive measure recommended in clinical practice to reduce the risk of this complication, typically involving heparin injection during the procedure in most centers. However, data on the effect of the timing of heparin injection are limited. The investigators hypothesize that injection of heparin before sheath insertion may reduce the rate of radial artery occlusion compared with injection after sheath insertion.
Eligibility criteria
Qualifiers
Patients having 18 years old or older, regardless of gender, undergoing percutaneous radial coronary intervention
Subject affiliated to a social protection health insurance
Subject able to understand the objectives and risks of the research and to provide dated and signed consent
Subject who has been informed of the results of the preliminary medical examination
Disqualifiers
Contraindication to the use of heparin (history of heparin-induced thrombocytopenia)
Very high bleeding risk defined by recent bleeding (<6 months) of type 3 of the BARC classification
Subject in an exclusion period (determined by a previous or ongoing study)
Inability to give the subject enlightened information (subject in an emergency situation, difficulties in understanding the subject, etc.)
Trial design
Treatments tested in this trial
- Administration of heparin after sheath insertion
- Administration of heparin prior to sheath insertion