TMJ Arthroscopy Compared to Arthrocentesis in Disc Displacement Without Reduction

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorKarolinska Institutet

About this trial

The goal of this clinical trial is to compare the intervention arthroscopic lysis and lavage to the intervention arthrocentesis in treating disabling and painful temporomandibular joint disc displacement without reduction. The main questions it aims to answer are:

* Which surgical method that best improves mouth opening capacity, TMJ pain, and TMJ disability? * If any pre- or peri-operative variable/-s could be identified as a predictor for surgical outcome? Researchers will compare arthroscopic lysis and lavage to arthrocentesis to see if arthroscopic lysis and lavage works better to treat temporomandibular joint disc displacement.

Participants will:

* Have one of the two interventions under general anesthesia, not knowing which intervention. * Visit an external clinic for regular checkups at 1, 3, 6, 12, and 24 months after surgery. * Answer three different quality of life surveys at the checkups.

Eligibility criteria

Qualifiers

Uni- or bilateral DDwoR affecting the patients mouth opening capacity to a range of ≤ 35 mm, verified with clinical and magnetic resonance imaging (MRI) findings.

TMJ pain ≥ 3 (NRS)

TMJ disability ≥ 3 (NRS)

Age ≥ 18 years

Disqualifiers

Prior open TMJ surgery

Patient diagnosed with rheumatologic joint disease.

ASA (American Society of Anaesthesiologists) > 3

Patient unable to verify informed consent.

Trial design

Treatments tested in this trial

  • Arthroscopic lysis and lavage
  • Arthrocentesis/Saline

Treatment groups

100 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Karolinska Institutet

Lead sponsor

Eastmaninstitutet

Collaborator

Karolinska University Hospital

Collaborator