Temporomandibular Joint Disc Displacement, Without Reduction

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Review clinical trials related to Temporomandibular Joint Disc Displacement, Without Reduction. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Arthroscopic Lysis and Lavage With and Without Intra-articular Injection of Hyaluronic Acid in Patients With DDwoR in TMJ

The study aims to assess the outcomes of arthroscopic lysis and lavage procedure with and without single intra-articular injection of hyaluronic acid in managing patients with anterior disc displacement without reduction. The research question that this study will answer is: Does arthroscopic lysis and lavage combined with hyaluronic acid provide better outcomes in terms of pain intensity and maximum mouth opening compared to arthroscopic lysis and lavage alone?

Participants needed: 52
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: May 29, 2026Locations: 1
Eligibility criteria

Adults above 18 years old. [+3]

Degenerative Temporomandibular Joint Disorders (e.g., osteoarthritis, rheumatoid... [+5]

Status: Recruiting

Long-term Follow up of TMJ Surgery and Evaluation of the 6-month Control as a Prognostic Marker.

The goal of this clinical trial is to evaluate the long-term outcome of surgical intervention (arthroscopy or discectomy) due to the diagnoses temporomandibular joint disc displacement with or without displacement. The main questions it aims to answer are: * Does the surgical outcome recorded at the earlier 6-month follow up persist at the long-term follow up approximately 10 years postoperatively? * How does the radiologically determined degree of joint degeneration change with time in patients that have had joint surgery? Researchers will compare the six-month surgical outcome to the ten-year outcome to see if temporomandibular joint surgery results are stable over time. Participants with an earlier performed joint surgery will: * Have a clinical examination approximately ten years postoperatively. * Have a temporomandibular joint x-ray scan performed (cone-beam computed tomography).

Participants needed: 91
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Karolinska InstitutetUpdated: Dec 17, 2025Locations: 1Duration: 10 Years
Eligibility criteria

Patients participating in the studies with ethical approval numbers EPN 2014/764... [+1]

Patient unable to verify informed consent.

Status: Recruiting

TMJ Arthroscopy Compared to Arthrocentesis in Disc Displacement Without Reduction

The goal of this clinical trial is to compare the intervention arthroscopic lysis and lavage to the intervention arthrocentesis in treating disabling and painful temporomandibular joint disc displacement without reduction. The main questions it aims to answer are: * Which surgical method that best improves mouth opening capacity, TMJ pain, and TMJ disability? * If any pre- or peri-operative variable/-s could be identified as a predictor for surgical outcome? Researchers will compare arthroscopic lysis and lavage to arthrocentesis to see if arthroscopic lysis and lavage works better to treat temporomandibular joint disc displacement. Participants will: * Have one of the two interventions under general anesthesia, not knowing which intervention. * Visit an external clinic for regular checkups at 1, 3, 6, 12, and 24 months after surgery. * Answer three different quality of life surveys at the checkups.

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Karolinska InstitutetUpdated: Jun 29, 2025Locations: 1
Eligibility criteria

Uni- or bilateral DDwoR affecting the patients mouth opening capacity to a range... [+3]

Prior open TMJ surgery [+3]