Total Knee Arthroplasty in Varus Deformity
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorI.M. Sechenov First Moscow State Medical University
About this trial
For the first time, a comparative analysis of the limb axis in patients with unilateral knee OA will be conducted compared to the contralateral uninjured side using Multisliced computed tomography (MSCT) and vertical CT (weight-bearing CT). This analysis will identify the pathological and physiological degrees of varus in patients with unilateral gonarthrosis. Indications for mechanical and kinematic limb axis alignment will be substantiated depending on the degree of varus deformity. Aim of the study: To improve the results of total knee arthroplasty in patients with varus deformity by optimizing the degree of varus correction. Objectives: To analyze physiological and pathological varus in patients with unilateral osteoarthritis under physiological loading. To develop an algorithm for applying various types of limb alignment.
Eligibility criteria
Qualifiers
Patients over 18 years of age with grade 3-4 knee osteoarthritis (according to Kellgren-Lawrence) and pain score of 5 or higher on a 10-point VAS scale.
Varus deformity of the lower limb (HKA angle <177°, or varus >3°)
Anesthesia risk according to the ASA scale of no more than III.
BMI less than 35 kg/m2.
Disqualifiers
Body mass index > 40 kg/m².
Instability of the collateral ligaments of the knee joint requiring the installation of ligamentous systems, presence of primary severe bone defects.
Impaired weight-bearing ability of the contralateral limb.
Presence of metal implants or foreign bodies in the lower extremities.
Trial design
Treatments tested in this trial
- Total knee arthroplasty using active robotic surgical system
- Total knee arthroplasty using active robotic surgical system
Treatment groups
300 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov