Knee Osteoarthritis in Varus

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Review clinical trials related to Knee Osteoarthritis in Varus. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Total Knee Arthroplasty in Varus Deformity

For the first time, a comparative analysis of the limb axis in patients with unilateral knee OA will be conducted compared to the contralateral uninjured side using Multisliced computed tomography (MSCT) and vertical CT (weight-bearing CT). This analysis will identify the pathological and physiological degrees of varus in patients with unilateral gonarthrosis. Indications for mechanical and kinematic limb axis alignment will be substantiated depending on the degree of varus deformity. Aim of the study: To improve the results of total knee arthroplasty in patients with varus deformity by optimizing the degree of varus correction. Objectives: To analyze physiological and pathological varus in patients with unilateral osteoarthritis under physiological loading. To develop an algorithm for applying various types of limb alignment.

Participants needed: 300
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: I.M. Sechenov First Moscow State Medical UniversityUpdated: Mar 12, 2026Locations: 1
Eligibility criteria

Patients over 18 years of age with grade 3-4 knee osteoarthritis (according to K... [+6]

Body mass index > 40 kg/m². [+6]