Transdiagnostic Internet-delivered Intervention for Adolescents With Anxiety and Depression

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age13-17
SponsorBabes-Bolyai University

About this trial

The goal of this clinical trial is to test the efficacy of a transdiagnostic Internet-delivered interventions for Romanian adolescents with anxiety and/ or depression. The main questions it aims to answer are:

* What is the clinical efficacy of the Internet-delivered intervention? * How accurate is the prediction model in predicting who will respond to treatment? Participants will undergo non-invasive fMRI to measure variability in brain signal as a proxy of the neural systems' adaptability before receiving the intervention, then they will be allocated either to the Internet-delivered intervention or control group.

Eligibility criteria

Qualifiers

elevated symptoms of anxiety or depression/ internalizing problems (T score> 60) at intake (based on Youth self-report completed by adolescents)

primary diagnosis of an anxiety/depressive disorder based on DSM-5 criteria according to ADIS-5-C/P interview

age 13-17

able to read and understand Romanian language

Disqualifiers

severe mental disorder (psychosis, severe depression, bipolar disorder, based on clinical interview)

any condition that interferes with the protocol implementation (e.g., physical illness or sensory impairment that interferes with behavioral tasks such as exposure, behavioral activation, unavailable for the next 3 months),

active suicidal ideation (assessed by child psychiatrist during clinical interview) in the last month

currently following CBT/ psychotherapy for anxiety/depression, in the last 6 months

Trial design

Treatments tested in this trial

  • Transdiagnostic Internet-delivered intervention

Treatment groups

198 Participants
are divided into 2 treatment groups

Sponsors and collaborators