About this trial
Patients suffering from sciatica are treated conservatively for the first 8 weeks due to the favourable prognosis. This period is preferably extended up to 14-16 weeks after which patients may opt for surgery. However, patients may experience severe discomfort due to pain in the leg which can lead to decreased physical activity and socio-economic problems. An adequate therapy to alleviate symptoms during this period of 'wait-and-see' is lacking. In this study, patients will be randomized to treatment with transforaminal epidural injections or standard oral pain medication.
Eligibility criteria
Qualifiers
Diagnosed with sciatica by GP
NRS leg pain of 6 or more on a 10-point NRS scale
Minimum duration of symptoms of 3 weeks and maximum duration of 8 weeks
Disqualifiers
Age under 18 years
Condition preventing to receive transforaminal epidural injection
Severe scoliosis
Transforaminal epidural injection received in 6 months before randomization date
Trial design
Treatments tested in this trial
- Lidocaine
- Methylprednisolone Acetate
- Dexamethasone
Treatment groups
Sponsors and collaborators
C.L.A.Vleggeert-Lankamp
Lead sponsor
Leiden University Medical Center
Sponsor institution
Spaarne Gasthuis
Collaborator
Stichting Achmea Gezondheidszor
Collaborator
Posthumus Meyjes Fonds
Collaborator