The objective is to understand the relationship between TP53 mutation, MSS and chromosome instability in endometrial cancer and the effect on clinical prognosis.We will collect a small amount of tumor tissue samples. NGS panel detection and WGD/AS analysis were performed on the tissue. Paracancer tissue was used as a negative control and relevant information in medical records during the operation. Then we will collect clinical diagnosis and disease information through telephone follow-up after the completion of the operation.
willing to participate in the study and sign the informed consent
age ≥18 years old
researchers evaluated that it was suitable to participate in this translational study
Endometrial cancer was confirmed histologically
Received chemotherapy within 14 days prior to sample collection, or received anti-tumor drug therapy such as radiotherapy, biotherapy, endocrine therapy, targeted therapy, immunotherapy, within 21 days prior to sample collection
previously treated with KIF18A inhibitors
researchers believed that the subjects were not suitable for the translational study for other reasons