Trial of Acceptance and Mindfulness-based Exposure Therapy (AMBET) and Present Centered Therapy (PCT)
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-81
SponsorColumbia University
About this trial
The goal of this clinical trial is to learn if a new therapy called Acceptance- and Mindfulness-Based Exposure Therapy (AMBET) helps treat post-traumatic stress disorder (PTSD) in people who survived a cardiac arrest. This study will compare AMBET to another psychotherapy treatment called Present Centered Therapy (PCT) to see which therapy is more effective in treating PTSD.
The main questions it aims to answer are:
Does AMBET reduce PTSD symptoms in survivors of cardiac arrest? How do the benefits of AMBET compare to PCT?
Participants will:
* Be randomly assigned to receive either AMBET or PCT * Attend 12 hours of individual psychotherapy sessions over about 12 weeks * Complete short weekly surveys about their mood and behaviors online * Wear a Fitbit device to track sleep and activity during the study * Do brief homework assignments between sessions
Eligibility criteria
Qualifiers
Between 18 and 81 years old at the time of consent
Fluency in English
Medical history of cardiac arrest >3 months ago
Clinically elevated PTSD symptoms (Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) score ≥25)
Disqualifiers
Lifetime history of primary psychotic or bipolar disorders
Current substance use disorder (moderate or severe in the past 6 months)
Active suicidal ideation with some intent to act in past 12 months, and/or suicide attempt in past 24 months
Substantial cognitive impairment (Mini Mental Status Exam (MMSE) score <25)
Trial design
Treatments tested in this trial
- Acceptance and Mindfulness Based Exposure Therapy
- Present-Centered Therapy
Treatment groups
90 Participants
are divided into 2 treatment groupsSponsors and collaborators
Columbia University
Lead sponsor
National Institute on Aging (NIA)
Collaborator
Source ClinicalTrials.gov