UltrasouNd-guided Percutaneous Intercostal Nerve Cryoneurolysis for Analgesia Following Traumatic Rib Fracture

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-100
SponsorSunnybrook Health Sciences Centre

About this trial

Traumatic rib fractures (i.e., broken ribs caused by a physical injury) are common and very painful. They also often lead to serious complications, more time spent in hospital, and can even lead to death. Even after rib fractures have healed, they can lead to long-term pain and a lower quality of life.

A technology called cryoneurolysis, which acts to freeze nerves causing pain using a small tool which can turn very cold, is a promising new way to manage rib fracture pain. This study is a test with a small number of people to see if it is feasible to use this technology for patients with rib fractures. If this is successful, we will recruit more people for a larger study to see if cryoneurolysis, along with standard pain control techniques, is better at stopping pain, compared to just the normal techniques alone. Participants in our study will be asked to rate their pain, and record pain medications that they take for 3 months after their pain procedure.

Eligibility criteria

Qualifiers

Aged ≥18

Unilateral traumatic rib fractures (3 to 8)

Candidate for ESP block catheter

Within 48hrs of admission to hospital

Disqualifiers

Lack of patient consent; unlikely to comply with follow up

Unable to use Patient Controlled Regional Analgesia (Ventilated/sedated patients or Moderate to severe traumatic brain injury)

Chronic pain (opioid use > 30mg oral morphine equivalent per day)

Substance use disorder

Trial design

Treatments tested in this trial

  • Cryoneurolysis
  • Sham Cryoneurolysis

Treatment groups

24 Participants
are divided into 2 treatment groups