Rib Fracture Multiple

7

Review clinical trials related to Rib Fracture Multiple. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Randomized Control Trial, Cryoablation as an Adjunct to Surgical Stabilization of Rib Fractures

To determine if patients with intraoperative cryoablation have better analgesia results compared to the control group of Surgical Stabilization of Rib Fractures (SSRF) without cryoablation

Participants needed: 80
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Wake Forest University Health SciencesUpdated: Jun 29, 2026Locations: 1
Eligibility criteria

The patient is admitted to the trauma service. [+4]

Age < 18 years or ≥ 80 years [+11]

Status: Not yet recruiting

Surgery for Unstable Chest Wall Injuries - How Many Fractures Should be Fixed?

The goal of this prospective, randomized study is to learn about the effects of two different surgical techniques for treating unstable chest wall injuries in adults. The main questions it aims to answer are: Does fixing two fractures per rib lead to better healing than fixing one fracture per rib in patients with unstable chest injuries? Does the choice of surgical method affect lung function, pain, other symptoms, risk of pneumonia, or the risk of complications? Participants will: * Undergo surgery using either the standard method (fixing one fracture per rib) or an alternative method (fixing two fractures per rib), both using a muscle-sparing technique. * Be followed up at 1, 3, and 12 months after surgery. * Have CT scans at 3 months (and at 12 months if healing is incomplete) to assess bone healing. * Be evaluated for lung function, pain, symptoms, and complications. This study aims to provide new knowledge about which surgical method is best for unstable chest wall injuries, helping to improve treatment and recovery for these patients.

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Sahlgrenska University HospitalUpdated: Apr 28, 2026Locations: 1
Eligibility criteria

Patients scheduled for surgery of acute (≤7 days after trauma) unstable injuries... [+1]

Patients with injuries resulting from CPR [+3]

Status: Recruiting

Zimmer Biomet-RibFix Titan

Prospective, single-center, non-randomized, single-cohort, post-market clinical follow-up study to confirm the safety, performance, and clinical benefits for the use of the RibFix Titan™ system implants and instrumentation) in the fusion, stabilization, and fixation of fractures in the chest wall including rib reconstructive surgical procedures, trauma, or planned osteotomies.

Participants needed: 54
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Zimmer BiometUpdated: Apr 21, 2026Locations: 1Duration: 1 Year
Eligibility criteria

At least 18 years of age [+2]

Midline Sternotomy: sternotomy incisions crossing the midline [+5]

Status: Not yet recruiting

Percutaneous Cryoablation of Intercostal Nerves for the Treatment of Rib Fractures

The goal of this double blinded randomized control trial is to learn if percutaneous cryoablation of traumatic rib fractures improves outcomes. The main questions it aims to answer are: Does percutaneous cryoablation improve short and long term pain scores? Does percutaneous cryoablation improve short and long term respiratory mechanics? Does percutaneous cryoablation improve long term quality of life? Does percutaneous cryoablation decrease delirium? Researchers will compare cryoablation to standard multimodal pain therapy to see if this impacts respiratory recovery. Participants will undergo randomization, percutaneous cryoablative procedure, and participate in tests at pre-determined intervals to evaluate their pulmonary recovery.

Participants needed: 30
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Loma Linda UniversityUpdated: Feb 9, 2026Locations: 1
Eligibility criteria

> 18 years old [+3]

Isolated Fractures of Ribs 1-3 and/or 10-12 [+18]

Status: Recruiting

UltrasouNd-guided Percutaneous Intercostal Nerve Cryoneurolysis for Analgesia Following Traumatic Rib Fracture

Traumatic rib fractures (i.e., broken ribs caused by a physical injury) are common and very painful. They also often lead to serious complications, more time spent in hospital, and can even lead to death. Even after rib fractures have healed, they can lead to long-term pain and a lower quality of life. A technology called cryoneurolysis, which acts to freeze nerves causing pain using a small tool which can turn very cold, is a promising new way to manage rib fracture pain. This study is a test with a small number of people to see if it is feasible to use this technology for patients with rib fractures. If this is successful, we will recruit more people for a larger study to see if cryoneurolysis, along with standard pain control techniques, is better at stopping pain, compared to just the normal techniques alone. Participants in our study will be asked to rate their pain, and record pain medications that they take for 3 months after their pain procedure.

Participants needed: 24
Trial details
Age: 18-100Biological sex: AllType: InterventionalSponsor: Sunnybrook Health Sciences CentreUpdated: Sep 12, 2025Locations: 1
Eligibility criteria

Aged ≥18 [+3]

Lack of patient consent; unlikely to comply with follow up [+9]

Status: Recruiting

Assessment of Morbidity and Mortality Following Serratus Anterior Plane Block (SAPB) for Unilateral Rib Fractures

The goal of this observational study is to learn about the long-term effects of the serratus anterior plane block (SAPB) in adult patients who suffered multiple unilateral anterolateral rib fractures within 24 hours of patient presentation to the emergency department. The main question it aims to answer is: Does the SAPB for multiple anterolateral rib fractures demonstrate reduction in patient morbidity and mortality, including incidence of pneumonia, length of hospital stay, discharge disposition, and death, as compared to standard analgesic regimens. The SAPB will be performed if a physician trained in the SAPB is available within 24 hours of injury. If a trained physician is not available and the patient meets inclusion criteria, they will receive parental analgesia with opioid therapy. They will be followed until date of hospital discharge, up until 60 days.

Participants needed: 220
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Albert Einstein College of MedicineUpdated: Aug 13, 2025Locations: 1
Eligibility criteria

Patients over 18 years of age being treated in the Emergency Department at Jacob... [+4]

Patients in traumatic arrest or hemodynamic instability [+8]

Status: Recruiting

Ultrasound Guided Serratus Anterior Plane Block for Rib Fractures

This study is a single center, randomized controlled trial examining the effect of serratus anterior plane block (SAPB) on pain, PIC scores and other clinical outcomes in emergency department patients with multiple rib fractures in comparison to the use of analgesic medication alone. Objectives 1. Compare SAPB performed in the ED setting to analgesic medication alone with regard to pain, respiratory status and PIC score of patients with multiple rib fractures. 2. Assess the safety and feasibility of performing ultrasound-guided SAPB in the ED. 3. Evaluate outcomes of patients receiving the SAPB in the ED including amount of analgesic medications used, level of care required, need for upgrading level of care, and length of stay.

Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: WellSpan HealthUpdated: Jul 18, 2025Locations: 1
Eligibility criteria

Age >18 years [+3]

Age <18 years [+5]