Urothelium Tissue Engineering Using Biopsies From Transurethral Resection of Prostate
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexMale
Age18+
SponsorCentral Hospital, Nancy, France
About this trial
Different clinical conditions can require urinary bladder augmentation or replacement. Tissue engineered bladder has been clinically evaluated but is not recommended due to diverse side effects. Thus, there is a real interest for the development of regenerative approach with innovative scaffolds and cell transplantation.
The investigators propose the use of urothelial cells obtained by Trans-Urethral Resection of Prostate or bladder (TURP) to obtain a tissue engineered urothelium in association with different scaffolds.
Eligibility criteria
Qualifiers
Patient needing a Transurethral Resection of Prostate (TURP)
Weight of prostate (evaluated by ultrasonography)greater than or equal to 30 grams
Affiliation to a social security system
Patient over the age of majority
Disqualifiers
Patient for whom no TURP is realized during endoscopic procedure
Patient for whom no resection is realized on the bladder neck
Patient with prostate weight estimated under 30 grams
Patient who opposed to the realization of the study
Trial design
Treatments tested in this trial
- Transurethral Resection of Prostate
Treatment groups
No treatment groups listed
Locations
Sponsors and collaborators
Source ClinicalTrials.gov