Bladder, Neurogenic

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Review clinical trials related to Bladder, Neurogenic. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Deceased Donor Bladder or Combined Kidney-bladder Transplantation: a Phase 0 First-in-human Study

The goal of this clinical trial is to demonstrate the feasibility of bladder transplantation in patients with terminal bladder diseases who would benefit from a new bladder or a combined kidney and bladder transplant. The main questions it aims to answer are: * Is human bladder transplantation feasible and safe? * How will the new bladder function in terms of storage and emptying? Participants will undergo a bladder-only or combined kidney and bladder transplantation. They will then be followed for two years to evaluate the efficacy, safety, and functionality of the bladder transplant.

Participants needed: 5
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: University of California, Los AngelesUpdated: Feb 12, 2025Locations: 1
Eligibility criteria

Age 18-70 years [+9]

HIV (active or seropositive), active hepatitis B or C, viral encephalitis, untre... [+12]

Status: Not yet recruiting

Urothelium Tissue Engineering Using Biopsies From Transurethral Resection of Prostate

Different clinical conditions can require urinary bladder augmentation or replacement. Tissue engineered bladder has been clinically evaluated but is not recommended due to diverse side effects. Thus, there is a real interest for the development of regenerative approach with innovative scaffolds and cell transplantation. The investigators propose the use of urothelial cells obtained by Trans-Urethral Resection of Prostate or bladder (TURP) to obtain a tissue engineered urothelium in association with different scaffolds.

Participants needed: 365
Trial details
Age: 18+Biological sex: MaleType: ObservationalSponsor: Central Hospital, Nancy, FranceUpdated: Oct 9, 2018
Eligibility criteria

Patient needing a Transurethral Resection of Prostate (TURP) [+4]

Patient for whom no TURP is realized during endoscopic procedure [+3]