Vision Loss Impact on Navigation in Virtual Reality

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age21-75
SponsorUniversity of Rochester

About this trial

The purpose of this research is to better understand the impact of cortically-induced blindness (CB) and the compensatory strategies subjects with this condition may develop on naturalistic behaviors, specifically, driving. Using a novel Virtual Reality (VR) program, the researchers will gather data on steering behavior in a variety of simulated naturalistic environments. Through the combined use of computer vision, deep learning, and gaze-contingent manipulations of the visual field, this work will test the central hypothesis that changes to visually guided steering behaviors in CB are a consequence of changes to the visual sampling and processing of task-related motion information (i.e., optic flow).

Eligibility criteria

Qualifiers

Residents of the United States or Canada

Presence of one-sided stroke or stroke-like damage to primary visual cortex or its immediate afferent white matter sustained within the specified age range of 21 - 75 years (verified by MRI and/or CT scans)

Reliable visual field defects in both eyes (homonymous defects) as measured by Humphrey or equivalent perimetry.

Willing, able, and competent to provide their own informed consent

Disqualifiers

Those who have never driven or earned a drivers' license

Past or present ocular disease interfering with visual acuity

Best corrected visual acuity (BCVA) worse than 20/40 in either eye

Sustained damage to the dorsal lateral geniculate nucleus

Trial design

Treatments tested in this trial

  • Virtual Reality Driving Task

Treatment groups

40 Participants
are divided into 2 treatment groups

Sponsors and collaborators

University of Rochester

Lead sponsor

Rochester Institute of Technology

Collaborator