Visual Plasticity Following Brain Lesions

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorGeorgetown University

About this trial

The VIBRANT (Vision Improvement through Behavioral Rehabilitation And Neuroplasticity Training) study is a prospective, double-blind, crossover design (within-subject) in participants with homonymous hemianopia-a type of visual field loss resulting from damage to the post-chiasmatic visual pathways. It aims to investigate whether transcranial random noise stimulation (tRNS) combined with perceptual learning-based training has potential for improving visual impairments.

Eligibility criteria

Qualifiers

At least 18 years of age.

Capable of providing informed consent and complying with study procedures.

Unilateral or bilateral focal brain damage causing loss of vision.

At least three months post-stroke or traumatic brain injury, or a stable brain tumor within the past year.

Disqualifiers

Severe CNS diseases or disorders unrelated to the focal lesion, which could interfere with study results.

Severe mental health challenges that could interfere with study results, or current or recent (within the past 6 months) drug or alcohol abuse or addiction as defined by DSM-5.

Vision loss resulting from ocular disease or disorder.

At least 18 years of age.

Trial design

Treatments tested in this trial

  • transcranial random noise stimulation (tRNS)
  • Sham Stimulation
  • Perceptual learning-based training

Treatment groups

30 Participants
are divided into 2 treatment groups

Sponsors and collaborators