About this trial
This research will explore if brain stimulation combined with virtual reality therapy improves visual impairment. The stimulation technique is called low-intensity focused ultrasound stimulation (LIFUS). The treatment uses ultrasound to stimulate vision specific parts of the brain. Before this therapy, the participants will get structural brain imaging. Functional brain imaging will be performed before and after the study's completion to measure brain activity response to therapy.
The purpose of this research study is to evaluate patients who have had a stroke between 6 and 24 months ago with a visual field impairment. The duration of active participation in the study is 1.5 months.
Eligibility criteria
Qualifiers
≥ 18 years old of any gender and race
Clinical ischemic stroke or hemorrhagic (confirmed by CT or MRI) that occurred >= 6-24 months ago
Partial or complete homonymous hemianopsia on clinical exam
Disqualifiers
Documented history of severe dementia with or without medication before stroke that affect subject's ability to participate in and be compliant to study protocol
Significant upper motor deficits and the subject cannot do IVR sessions at the baseline
History of seizures
Inability to get a new MRI
Trial design
Treatments tested in this trial
- Low-intensity focused ultrasound
- Immersive virtual reality
- Inactive Low-intensity focused ultrasound