Whole-Brain Dynamics in the Natural Menstrual Cycle vs. an Ovarian Stimulated Cycle: Impact of Hormonal Fluctuations on Healthy Women Undergoing Ovarian Stimulation

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age25-35
SponsorART Fertility Clinics LLC

About this trial

The investigators aim is to investigate the brain's dynamic complexity across three phases of an ovarian stimulation cycle (basal, pre-OPU, mid-luteal), to observe the impact of externally administered hormones, and compare it with the corresponding phases of a natural menstrual cycle (early follicular, pre-ovulatory, mid-luteal) in the same woman. Brain activity patterns will be examined using resting-state fMRI in a sample of young, healthy, naturally cycling women.

Eligibility criteria

Qualifiers

Age group: 25 - 35 years old

BMI: 20 - 30

Anti-Mullerian Hormone (AMH): 1.3 - 5.9 ng/ml

Regular Menstrual Cycle: 26-35 days

Disqualifiers

History of ovarian surgery

Pathology of the ovaries

Mental health disorders

Use of medication influencing brain function

Trial design

Treatments tested in this trial

  • Functional Magnetic resonance imaging will be done on day 2 or 3 of the menstrual cycle, trigger-shot and egg retrieval.

Treatment groups

15 Participants
are divided into 1 treatment group

Sponsors and collaborators

ART Fertility Clinics LLC

Lead sponsor

Khalifa University for Science and Technology

Collaborator

New York University Abu Dhabi

Collaborator