Adductor Canal Block

7

Review clinical trials related to Adductor Canal Block. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Comparison of Two Different Regional Anesthetic Methods in Total Knee Arthroplasty Patients

Total Knee Arthroplasty patients are among the orthopedic cases that experience severe postoperative pain. In these cases, pain must be controlled. If pain is not controlled, early mobilization cannot be achieved. This can result in delayed physical therapy, prolonged hospital stays, the development of nosocomial infections, and impaired cognitive function. All of these factors contribute to increased patient care costs. Multimodal analgesia methods are used to control this pain. One of these methods is peripheral nerve blocks. Peripheral nerve blocks provide pain control and reduce the likelihood of opioid use and related side effects such as nausea, vomiting, and constipation. Current studies recommend Adductor Canal Blocks and iPACK (space between the popliteal artery and the posterior knee capsule) blocks for Total Knee Arthroplasty patients. In addition, studies are also being conducted on the application of the Suprainguinal Fascia-Iliaca Block in Total Knee Arthroplasty patients. The differences in postoperative analgesic effects between these methods are a matter of interest. No study has been conducted comparing the effects of these two approaches, which are routinely applied in our clinic and comply with guidelines, on the postoperative stress response. Regional anesthesia provides adequate pain control and has a positive effect on the stress response. The investigators aim to see a similar effect in peripheral nerve blocks. Therefore, comparing the methods that mentioned will contribute to the literature. In this study, the effects of these two different approaches on postoperative stress response and analgesic efficacy will be compared in terms of patients' postoperative opioid consumption, pain at rest and with movement, time to first analgesic need and development of motor block. IL-6 and CRP values will be examined pre-operatively and post-operatively to measure the effects on the stress response.

Participants needed: 52
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: SB Istanbul Education and Research HospitalUpdated: Apr 6, 2026Locations: 1
Eligibility criteria

Patients undergoing total knee arthroplasty [+2]

Coagulation disorders [+10]

Status: Not yet recruiting

Adductor Canal Block Methods in Bilateral Total Knee Arthroplasty

This study aims to compare the analgesic efficacy of surgeon-performed intraoperative adductor canal block (ACB) and ultrasound-guided anesthesiologist-performed ACB in patients undergoing bilateral total knee arthroplasty (TKA). In a prospective, randomized paired design, each patient will receive surgeon-performed ACB on one knee and anesthesiologist-performed ACB on the contralateral knee. The primary outcome is postoperative pain measured using the Numeric Rating Scale (NRS), and the study is designed to evaluate the non-inferiority of surgeon-performed ACB. Secondary outcomes include opioid consumption, time to first ambulation, length of hospital stay, postoperative complications, and patient-reported outcome measures (PROMs). Additionally, postoperative ultrasound evaluation will be performed to assess the distribution pattern of local anesthetic within the adductor canal, including cross-sectional area and longitudinal spread. This study is expected to provide evidence regarding the clinical effectiveness and technical accuracy of surgeon-performed ACB in comparison with the conventional ultrasound-guided technique.

Participants needed: 48
Trial details
Age: 60+Biological sex: AllType: InterventionalSponsor: Yonsei UniversityUpdated: Apr 1, 2026
Eligibility criteria

Adult patients aged 19 years or older [+2]

Refusal to participate or inability to provide informed consent [+6]

Status: Recruiting

Enhanced Recovery After Major Surgery and Chronic Pain for Total Knee Arthroplasty

The goal of this interventional clinical trial is to assess opioid consumption 24-48 hrs post anesthesia block among patients undergoing total knee arthroplasty. The main question it aims to answer is: 1\. Is there a difference in opioid consumption 24-48 hours post block administration among patients that receive an adductor canal catheter (ACC) versus adductor canal block (ACB)? Participants will be: * Randomized to receive an adductor canal catheter (ACC) or a sham adductor canal catheter. * Asked to use the Diagnotes application to communicate with the pain doctor while the catheter is in place. * Follow up for up to 6 months post-operation. Researchers will compare the interventional group (ACC) to the control group (sham ACC + ACB) to see if there is difference in opioid consumption and chronic pain at 6 months post-operation.

Participants needed: 64
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: Hospital for Special Surgery, New YorkUpdated: Jan 15, 2026Locations: 1
Eligibility criteria

Patients with osteoarthritis scheduled for a primary total knee arthroplasty wit... [+7]

Hepatic or renal insufficiency [+13]

Status: Not yet recruiting

Postoperative Analgesic Efficacy Between Adductor Canal Block + IPACK Block and Adductor Canal Block + Genicular Nerve Block in Total Knee Arthroplasty

The aim of this study is to compare the postoperative analgesic efficacy and functional outcomes of the IPACK+Adductor Canal Block with the Genicular Nerve Block+Adductor Canal Block block in patients undergoing total knee arthroplasty (TKA). The primary objective (measurable) is to evaluate functional improvement using 6-Clicks scores, while secondary objectives include pain scores (Vas Score), opioid consumption, hospital stay duration, and patient satisfaction (Patient Satisfaction Index). IPACK : The infiltration between the popliteal artery and capsule of the knee

Participants needed: 50
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Konya Beyhekim Training and Research HospitalUpdated: Jan 7, 2026
Eligibility criteria

Patients scheduled for spinal anesthesia with TDA. [+3]

Active infection at the injection site. [+5]

Status: Not yet recruiting

Adductor Canal Localization in Living and Cadaver

The aim of this study is to define the starting and ending points of the adductor canal in adductor canal block (ACB) applications through distance measurements relative to the anterior superior iliac spine (ASIS) and the adductor tubercle. These measurements are performed using ultrasound (USG) and correlated with cadaveric data. Key research questions addressed include: * Can the start and end points of the adductor canal be formulated along a line drawn between the ASIS and the adductor tubercle? * Is there a definable relationship between the block application site and anatomical landmarks such as the vastoadductor membrane (VAM), the apex of the femoral triangle, and other adjacent structures that facilitates localization? By validating ultrasound measurements with cadaveric findings, the study aims to provide researchers with a more predictable and reliable method for determining the optimal site for adductor canal block administration.

Participants needed: 200
Trial details
Age: 18-65Biological sex: AllType: ObservationalSponsor: Ankara Etlik City HospitalUpdated: Nov 25, 2025Locations: 1
Eligibility criteria

Not listed

Status: Not yet recruiting

Coupling of IPACK Block With Adductor Canal Block Versus Adductor Canal Block Alone on Pain, Functional Recovery and Inflammatory Response After Knee Replacement

The aim of this study is to compare the Competency of coupling of IPACK Block with Adductor Canal Block versus Adductor Canal Block Alone on Postoperative Pain after total knee replacement as well as Functional Recovery and Inflammatory Response and range of motion postoperatively.

Participants needed: 50
Trial details
Age: 20-70Biological sex: AllType: InterventionalSponsor: Ain Shams UniversityUpdated: Jul 31, 2025
Eligibility criteria

Patients undergoing total knee replacement. [+3]

Patients undergoing bilateral or revision total knee replacement. [+9]

Status: Recruiting

Combined Intrathecal Dexmedetomidine and Adductor Canal Block for Analgesia After Total Knee Arthroplasty

The aim of this work is to evaluate the effect of combined intrathecal dexmedetomidine and adductor canal block for analgesia after total knee arthroplasty (TKA).

Participants needed: 75
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: Kafrelsheikh UniversityUpdated: Feb 21, 2025Locations: 1
Eligibility criteria

Age from 18 to 75 years. [+3]

Patients with neurological or intellectual disability. [+6]