Biomechanics

6

Review clinical trials related to Biomechanics. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

"Balance, Gait, and Motion Analysis in Multiple Sclerosis"

The goal of this observational cross-sectional study is to investigate the relationship between functional measures of balance and gait and objective kinetic and kinematic parameters in people with Multiple Sclerosis (MS). The main questions it aims to answer are: i) What is the relationship between kinetic and kinematic gait and balance parameters measured using the Vicon motion analysis system and performance on clinical functional assessments in people with Multiple Sclerosis? ii) Which biomechanical parameters are most strongly associated with functional balance, gait, and physical performance outcomes? Participants will attend a single laboratory-based assessment session. During this session, they will undergo biomechanical gait and balance analysis using the Vicon motion capture system, complete functional assessments of balance, gait, and physical performance, complete questionnaires assessing fear of falling and fatigue, and undergo assessment of lower-limb spasticity.

Participants needed: 40
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: University of PatrasUpdated: Jun 24, 2026Locations: 2
Eligibility criteria

Adults (≥ 18 years) with confirmed diagnosis of Multiple Sclerosis [+4]

History of injury or surgical intervention to the lower limbs or spine within th... [+2]

Status: Recruiting

Effects of Hip-Assist Exoskeleton Torque on Gait Parameters

This study aims to evaluate the impact of assistive torque from a hip-assist exoskeleton on gait patterns in healthy adults. The investigators will analyze how different torque settings affect spatiotemporal parameters, joint kinematics, muscle activity (EMG), and foot pressure during walking.

Participants needed: 15
Trial details
Age: 19+Biological sex: AllType: InterventionalSponsor: Yonsei UniversityUpdated: Mar 5, 2026Locations: 1
Eligibility criteria

Healthy adults aged 19 years or older without gait impairment. [+4]

Skin or musculoskeletal issues that prevent wearing the exoskeleton. [+2]

Status: Recruiting

Effects of Single Sodium Bicarbonate Supplementation on National-Level Finswimming Performance

This randomized, double-blind, placebo-controlled crossover trial will investigate the acute effects of sodium bicarbonate supplementation on performance, stroke biomechanics, and selected physiological and perceptual responses during a simulated 200-meter Bi-Fins race in elite finswimmers.

Participants needed: 20
Trial details
Age: 15-30Biological sex: AllType: InterventionalSponsor: Palacky UniversityUpdated: Aug 22, 2025Locations: 1
Eligibility criteria

Member of a wider national selection in finswimming (junior or senior level) [+5]

History of gastrointestinal disorders affecting supplement tolerance [+4]

Status: Recruiting

Biomechanical Validation of the CATT

As of 2020, 53 million Americans provide unpaid care to an individual with a disability. One commonly performed activity of daily living (ADL) provided by informal caregivers is assisted transfers, which requires moving an individual from one surface to another. Approximately 94% of informal caregivers who assist with ADLs to persons with adult-onset chronic physical disabilities affecting mobility reported musculoskeletal discomfort, with pain and discomfort made worse by performing caregiving activities. Although many informal caregivers assist with transfers, most have never received any formal training in proper manual lifting or mechanical lifting techniques. Improper transfer techniques can be detrimental to not only caregiver health but also to the persons they assist resulting in shoulder injury, bruising and pain from manual lift techniques, hip fractures from falls, and skin tears from shear force that occurs with sliding during transfers. Current standard of care provides limited in-person training of caregivers, as most of the rehabilitation process is client-focused. When training is provided clinicians have no means to objectively evaluate if proper techniques are being performed at discharge or when the caregiver and care recipient return home. For this reason, an outcome measure called the Caregiver Assisted Transfer Technique Instrument (CATT) was developed to provide a quick, objective way to evaluate proper technique of caregivers who provide transfer assistance to individuals with disabilities. The CATT evaluates the caregiver's performance on setup, quality of the task performance, and results. After a formal assessment through stakeholder review involving clinicians, informal caregivers, and individuals with physical disabilities who require transfer assistance, the CATT was expanded to include two versions; one that evaluates manual lift technique (CATT-M) and one that evaluates mechanical lift techniques (CATT-L). However, the CATT must undergo further testing with informal caregivers and the individuals they assist to determine if the CATT is a reliable, valid, and responsive tool for identifying skill deficits in caregivers performing assisted transfers. The purpose of this study is to establish the psychometric properties (reliability, validity, and responsiveness) of the CATT and to evaluate the effects of an individualized training session for participants who have transfer technique deficits as identified by the CATT. The long-term goal of this research is to develop the CATT so that it can be used as an objective indicator of transfer performance as well as guide training and educational interventions for informal caregivers to reduce the risk of musculoskeletal pain and injury associated with assisted transfers.

Participants needed: 160
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: VA Office of Research and DevelopmentUpdated: Jul 30, 2025Locations: 1
Eligibility criteria

at least 18 years old [+7]

have existing pressure ulcers or a recent history of pressure ulcers within the... [+1]

Status: Recruiting

Non-invasive Imaging Technique for the Study of Lordosis in Pregnant Women and Its Relationship to Birth Outcome

The study consists of collecting measurement data of the rachis in pregnant women and the subsequent outcome of her delivery. This will make it possible to validate a non-invasive imaging technique through software that can be used to study this anatomical curve proposing a new measurement method for the angle of lordosis. Finally, with the research data, the investigators will try to find a correlation between these variables (angle of lordosis and delivery outcome.

Participants needed: 122
Trial details
Age: 20-40Biological sex: FemaleType: ObservationalSponsor: University of AlcalaUpdated: Nov 8, 2024Locations: 1
Eligibility criteria

pregnant women between 20 and 40 years old with a low-risk pregnancy

Pregnant women under 20 years and over 40 years of age or with a significant lum...

Status: Recruiting

HIIT vs MICT During Pregnancy and Health and Birth Outcomes in Mothers and Children

Regular exercise during pregnancy and postpartum leads to health benefits for mother and child. Inactivity during pregnancy and after delivery is now treated as risky behavior. Physically active pregnant women significantly less often suffer from, among others, gestational diabetes, excessive weight gain, lipids disorders, hypertension, preeclampsia, depressive symptoms, functional and structural disorders, including stress urinary incontinence, back pain or diastasis recti abdominis (DRA). Prenatal physical activity reduces the risk of premature delivery and miscarriage, fetal macrosomia, complications in labor or the risk of metabolic disorders in children. High-intensity interval training (HIIT) has become one of the most popular trends in the fitness sector. The effectiveness of HIIT on a number of health indicators has been proven in various populations but limited data are available on HIIT during pregnancy. The first hypothesis is that the HIIT, implemented during pregnancy and after childbirth, as a stronger exercise stimulus, will have a better impact on selected biological and psychological parameters of mothers, as well as on selected health parameters of their children, compared to the MICT (moderate intensity continuous training). Therefore, it promises better preventive effects on pregnancy complications and ailments as well as non-communicable diseases occurring in these populations. In the second hypothesis, it was assumed that HIIT and MICT implemented during pregnancy and after childbirth, tailored to the specific needs of the perinatal period, will not differ in the effectiveness of maintaining normal functional parameters in women, including prevention of urinary incontinence, back pain, DRA, etc. Pregnant women who apply for the study will be divided into three groups: those attending the HIIT, MICT or educational programs. During the study, the participants will be under standard obstetric care. As comparative groups, non-pregnant women will be also recruited. The investigators will collect data on selected biological, functional and psychological parameters in the study women at each trimester of pregnancy, during the puerperium and one year after childbirth. The data from the medical documentation on the course of childbirth and the assessment of the new-born, as well as the results of preventive examinations in the study women's children aged one, two, four and six years will be also analyzed.

Participants needed: 600
Trial details
Age: 18-45Biological sex: FemaleType: InterventionalSponsor: Gdansk University of Physical Education and SportUpdated: Dec 2, 2022Locations: 1
Eligibility criteria

course of pregnancy allowing participation in physical activities adapted to pre... [+12]

contraindications to increased physical effort or to any of the diagnostic or co... [+2]