Bipolar Disorder, Type 1

1

Review clinical trials related to Bipolar Disorder, Type 1. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Use of Ketosis in Modulating Metabolic Pathways in Bipolar Disorder

The goal of this clinical trial is to test how specific components of diet affect brain function and behavior for individuals with bipolar. The main question it aims to answer is how glucose and ketones each affect the brain's response to risk and reward. Participants will be asked to provide blood (to assess baseline measures of how the body uses energy), and then to receive two MRI scan sessions, on separate days. During each MRI scan session, participants will play three games, from which they can win money, before and after drinking glucose (on one day) or ketones (on the other day). Investigators will compare individuals with and without bipolar to test whether the two groups differ in how their brains use energy, and to test how the brain's use of energy affects behavior.

Participants needed: 100
Trial details
Age: 18-45Biological sex: AllType: InterventionalSponsor: Stony Brook UniversityUpdated: Apr 15, 2026Locations: 3
Eligibility criteria

Bipolar disorder diagnosis: Patients must have a Diagnostic Statistical Manual (... [+25]