Cancer of the Pancreas

3

Review clinical trials related to Cancer of the Pancreas. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma

The investigators hypothesize that MK2 inhibition may improve efficacy of mFOLFIRINOX chemotherapy for patients with pancreatic ductal adenocarcinoma (PDAC).

Participants needed: 51
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Washington University School of MedicineUpdated: Apr 30, 2026Locations: 1
Eligibility criteria

Histologically or cytologically confirmed pancreatic ductal adenocarcinoma with... [+14]

A history of other malignancy with the exception of 1) malignancies for which al... [+14]

Status: Recruiting

Stereotactic Body Radiotherapy Plus FAK and RAF/MEK Inhibition in Advanced Pancreatic Adenocarcinoma

Advanced pancreatic cancer patients receiving treatment of adaptive stereotactic body radiotherapy (SBRT) with concurrent and adjuvant defactinib plus avutometinib will have increased progression-free survival (PFS) compared to historical PFS rates for patients receiving adaptive SBRT alone.

Participants needed: 36
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Washington University School of MedicineUpdated: Apr 15, 2026Locations: 1
Eligibility criteria

Histologically or cytologically confirmed advanced pancreatic adenocarcinoma tha... [+19]

A history of other malignancy with the exception of prior or concurrent malignan... [+30]

Status: Recruiting

MicroEnvironment Tumor Effects of Radiotherapy - Comprehensive Radiobiology Assessment TRial

This study is a dynamically adjustable prospective longitudinal study designed to capture biospecimen (biopsy, blood, surgical) and multimodal treatment-related data (imaging, dosimetry, clinical) before, during, and after treatment with definitive-intent chemoradiotherapy for patients with locally advanced cervical and pancreatic cancer.

Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Washington University School of MedicineUpdated: Nov 12, 2025Locations: 1
Eligibility criteria

Cervical cancer [+4]

Any issue (medical, anatomic, other) that might preclude safe acquisition of bio...