Caries Active

5

Review clinical trials related to Caries Active. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Bioceramic Putty Versus MTA in Pulpotomized Primary Teeth to be Covered With 3D Printed Resin Crowns Versus Stainless Steel Crown

children aged 5 to 7 years with deep carious second primary molars that require vital pulp therapy will be treated using either MTA or bioceramic putty, then will be fully covered using either stainless steel crowns or 3D printed resin crowns.

Participants needed: 60
Trial details
Age: 5-7Biological sex: AllType: InterventionalSponsor: Alexandria UniversityUpdated: Jan 15, 2026Locations: 1
Eligibility criteria

Children aged from 5 to 7 years. 2. Medically healthy children (ASA I) (Appendix... [+4]

History of spontaneous pain. 2. Tooth mobility. 3. Excessive bleeding from radic...

Status: Not yet recruiting

Anxiety During Caries Removal Using Chemo-mechanical Versus Conventional Methods

This study aims to clinically assess this newly introduced Egyptian chemo-mechanical caries removal gel versus conventional drilling method . The concept of preserving healthy tooth structures and employing atraumatic restorative techniques during cavity preparation aligns with the principles of minimally invasive dentistry. This approach prioritizes patient comfort, reassurance, and fosters a positive perception of dental treatment.

Participants needed: 80
Trial details
Age: 10-25Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Jan 15, 2026Locations: 1
Eligibility criteria

Open carious lesions with dentin involvement, but not involving the pulp in lowe... [+4]

Patients with spontaneous or elicited pain from caries. [+7]

Status: Not yet recruiting

the Effect of Monk Fruit and Splenda on Salivary Ph and Streptococcus Mutans Count in Vivo Study

This study aims to evaluate the changes in salivary pH and Streptococcus mutans count by preparing a solution containing these sweeteners dissolved in distilled water and administering it to the participants. Saliva samples will be collected before using the mouth rinse, and salivary pH will be measured using a pH meter, while S. mutans count will be analyzed in the laboratory. After consuming the solution, salivary pH will be assessed at 1 minute, 15 minutes, and 30 minutes, while the growth of S. mutans will be examined 30 minutes post-rinse.

Participants needed: 90
Trial details
Age: 20-24Biological sex: AllType: InterventionalSponsor: Al-Mustansiriyah UniversityUpdated: Sep 24, 2025Locations: 1
Eligibility criteria

No active carious lesions or oral diseases. [+2]

Participants currently undergoing dental treatment. [+2]

Status: Not yet recruiting

Clinical Effectiveness of Bioactive Silica Based With Calcium Toothpaste

This study will be conducted to Clinically evaluate Bioactive Silica Based with calcium booster (Refix technology) toothpaste and Sodium Fluoride varnish versus conventional fluoride toothpastes in management of white spot lesions of adult patients over 6m follow up and evaluating patient perception regarding the treatment provided.

Participants needed: 20
Trial details
Age: 22-55Biological sex: AllType: InterventionalSponsor: Rawda Hesham Abd ElAzizUpdated: Aug 13, 2025
Eligibility criteria

Patient with non cavitated carious WSL in at least one upper or lower tooth. [+1]

Presence of surface cavitation or restorations .

Status: Not yet recruiting

Surface Caries Feature Study

Dental caries (dental cavity) is very common and can impact oral health and oral health-related quality of life. Dental caries is when the tooth surfaces break down, and if left untreated, can cause tooth pain. In routine clinical practice, dental professionals typically assess caries lesions by looking at patients' teeth, touching the areas of interest with a dental probe, and running a probe over the teeth to check the buildup of bacteria. Dentists often use x-rays to help find cavities, and they can also take pictures of the teeth to show what the problem looks like. New tools called intraoral scanners are becoming more useful for finding cavities. These scanners do not use radiation and do not hurt. Some computer programs that use artificial intelligence (AI) can also help dentists find cavities. AI can study the spots on patients' teeth and help make better, faster decisions. The purpose of this study is to collect data that will be used to develop and test an AI software that can help dentists in the detection of caries.

Participants needed: 88
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: 3Shape A/SUpdated: Jul 2, 2025
Eligibility criteria

Willing and able to give informed consent for participation in the study [+6]

Patients with orthodontic appliances and permanent retainers [+3]