Central Nervous System Neoplasm

6

Review clinical trials related to Central Nervous System Neoplasm. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Studying the Workflow of the American College of Surgeons Geriatric Surgery Program to Improve Clinical Outcomes in Older Adults Undergoing Surgery at the James Cancer Hospital

This study examines how the American College of Surgeons Geriatric Surgery Verification Program, also called the ACS GSV Program, is implemented at the James Cancer Hospital. The program is designed to improve surgical care for adults age 65 and older by helping care teams identify and address age-related needs before, during, and after surgery. Older adults with cancer may have concerns related to physical function, memory or thinking, medications, social support, and goals of care. If these needs are not recognized, patients may be at higher risk for complications, longer hospital stays, readmission, or discharge to a facility instead of home. The ACS GSV Program includes standards for geriatric surgery leadership, goals-of-care discussions, screening for age-related vulnerabilities, care plans for identified needs, age-friendly perioperative care, and regular review of surgical outcomes. This study will evaluate how well these standards are adopted across surgical oncology services and whether implementation is associated with better outcomes, such as shorter hospital stays, fewer complications, fewer readmissions, and improved discharge outcomes. The results may help improve surgical care workflows for older adults undergoing cancer surgery.

Participants needed: 4,000
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Ohio State University Comprehensive Cancer CenterUpdated: May 29, 2026Locations: 1
Eligibility criteria

Patient records for adults aged 65 years or older [+3]

Patient records for encounters occurring only at outside institutions or non-Jam... [+3]

Status: Recruiting

Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer Survivors

This study assesses how personal relationships (such as friendships, family relationships, or romantic partners) influence the physical activity (exercise) and well-being of young adult cancer survivors. Researchers also hope to learn how social relationships change after a cancer diagnosis, and how these changes might impact important health behaviors. The information provided may help researchers learn more about better ways to support young cancer patients in the future through interventions that help maintain good social relationships and health levels of physical activity.

Participants needed: 250
Trial details
Age: 18-39Biological sex: AllType: ObservationalSponsor: University of Southern CaliforniaUpdated: May 28, 2026Locations: 2
Eligibility criteria

Diagnosed and/or treated with cancer between ages 18-39 at USC hospitals. [+3]

Diagnosis of blood malignancies such as leukemias (these cancers have divergent... [+2]

Status: Recruiting

Project: Every Child for Younger Patients With Cancer

This study gathers health information for the Project: Every Child for younger patients with cancer. Gathering health information over time from younger patients with cancer may help doctors find better methods of treatment and on-going care.

Participants needed: 75,000
Trial details
Age: Up to 25Biological sex: AllType: ObservationalSponsor: Children's Oncology GroupUpdated: May 5, 2026Locations: 278
Eligibility criteria

Enrollment must occur within 6 months of initial disease presentation OR within... [+17]

Status: Recruiting

Cerebrospinal Fluid Biomarkers for Brain Tumors

This study examines cerebrospinal biomarkers in patients with brain tumors. A biomarker is a measurable indicator of the severity or presence of your disease state. Collecting and storing samples of cerebrospinal fluid from patients with brain tumors to study in the laboratory may help doctors develop new strategies to better diagnose, monitor, and treat brain tumors.

Participants needed: 400
Trial details
Biological sex: AllType: ObservationalSponsor: Mayo ClinicUpdated: Apr 22, 2026Locations: 1
Eligibility criteria

Any evidence of neoplasm involving the central nervous system (CNS) or its adjac... [+1]

Patients who are under 18 years of age or are a member of a vulnerable populatio... [+5]

Status: Recruiting

Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-Oncology

This study evaluates patient perceptions around quality of care through telemedicine in neuro-oncology. Studying questionnaires related to perceptions quality of care through telemedicine in patients with brain cancer may help doctors to improve the delivery of care through this modality.

Participants needed: 200
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: M.D. Anderson Cancer CenterUpdated: Mar 5, 2026Locations: 1
Eligibility criteria

Patients with a CNS tumors: this includes patients with primary brain tumors, br... [+3]

Encounter occurred with the assistance of official language translation support [+3]

Status: Recruiting

Gadolinium and Ferumoxytol MRI in Diagnosing Patients With Abnormalities in the Central Nervous System

This phase II trial studies how well gadolinium and ferumoxytol magnetic resonance imaging (MRI) work in diagnosing patients with abnormalities in the central nervous system. Diagnostic procedures, such as gadolinium and ferumoxytol MRI, may help find and diagnose abnormalities in the central nervous system.

Participants needed: 150
Trial details
Phase: Phase 2Age: 10+Biological sex: AllType: InterventionalSponsor: OHSU Knight Cancer InstituteUpdated: Feb 27, 2026Locations: 1
Eligibility criteria

Neurological findings (i.e. headache, loss of consciousness, paresis, cranial ne... [+6]

Subjects with clinically significant signs of uncal herniation, such as acute pu... [+6]