Dental Restoration

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Review clinical trials related to Dental Restoration. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Additive vs Subtractive Manufacturing for Endocrown Fabrication: A 24-Month RCT

This randomized controlled trial (RCT) compares the 24-month clinical performance of endocrown restorations fabricated by two digital manufacturing pathways: additive manufacturing using 3D-printed ceramic-filled photopolymer resin (VarseoSmile TriniQ, BEGO) versus subtractive computer-aided design/computer-aided manufacturing (CAD/CAM) milling from hybrid nano-ceramic blocks (HC Hard Block, Shofu). Sixty endocrowns will be placed in endodontically treated posterior molars and evaluated using modified United States Public Health Service (USPHS) criteria at 6, 12, and 24 months. The trial is conducted at the Conservative Dentistry Department, Faculty of Dentistry, Cairo University.

Participants needed: 60
Trial details
Age: 25-45Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Jun 8, 2026
Eligibility criteria

Age 25-45 years, male or female [+6]

Diagnosed parafunctional habit or nocturnal bruxism [+8]

Status: Recruiting

3M(TM) Filtek(TM) Supreme Flowable Composites for Class IV and Veneers

This clinical study aims to evaluate the clinical performance of 3M™ Filtek™ Supreme Flowable Composite in class IV and veneer indication. Follow-ups of 7 days, 6, 12, and 24 months will be conducted following an Fédération Dentaire Internationale (FDI) modified score (2023). A minimum of 50 Class IV and 25 veneers will be included in the evaluation. Research data and pictures will be provided for each patient pre-op and at 7 days (baseline, 6 months, 12 months and 24 months. Evaluation will be conducted by two calibrated evaluators different from the operator according to FDI clinical criteria.

Participants needed: 75
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: New York UniversityUpdated: Feb 27, 2026Locations: 1
Eligibility criteria

Age between 18 -75 years old [+6]

Single tooth veneers [+18]

Status: Not yet recruiting

Prosthetic Outcomes and Clinical Performance of Implant Supported Zirconia Crowns

To compare biological, technical, radiographic, and patient-reported outcomes of two types of monolithic zirconia crowns screw-retained to implant. To assess whether the new form of multilayered zirconia crowns will show similar survival and success rate to conventional monolithic Zirconia screw-retained to implants in molar and premolar regions. First Null Hypothesis: Multilayered monolithic zirconia crowns would have similar survival, success rate compared to conventional monolithic zirconia implant supported crowns. Second Null hypothesis: There would be no difference in clinical and patients related outcomes between multilayered and conventional monolithic zirconia implant supported crowns.

Participants needed: 40
Trial details
Age: 18-60Biological sex: AllType: InterventionalSponsor: University of JordanUpdated: Apr 1, 2025Locations: 1
Eligibility criteria

Partially edentulous area with suitable restorative space more than 5.5 mm [+6]

Inability to provide consent. [+3]

Status: Recruiting

Comparative Clinical Evaluation of BioFlx, Zirconia, and Stainless-Steel Crowns in Primary Molars

This study will be conducted to: Evaluate and compare the clinical success, periodontal changes, and wear of antagonist teeth for three types of prefabricated crowns in primary molars: BioFlx crowns, Zirconia crowns, and Stainless Steel crowns.

Participants needed: 51
Trial details
Age: 4-7Biological sex: AllType: InterventionalSponsor: Mansoura UniversityUpdated: Jun 10, 2024Locations: 1
Eligibility criteria

Children who are free from any systemic disease. [+3]

Children with extremely poor oral hygiene. [+3]