Edentulous Mouth

7

Review clinical trials related to Edentulous Mouth. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Changes in Microbial Status From Dentate, Edentulous and After Dental Implant Placement

The objectives of this study are to analyze the oral microbiome modulations occurring during the transition from partial (with some residual teeth) to full edentulous (without remaining teeth) status and implant placement in subjects affected by severe periodontitis; to evaluate if microbiome changes in relation to the used of different implant material/surface; and to assess the variance of the changes to determine the sample size for future longitudinal prospective studies.

Participants needed: 12
Trial details
Age: 21+Biological sex: AllType: ObservationalSponsor: Case Western Reserve UniversityUpdated: Jul 1, 2026Locations: 1
Eligibility criteria

At least 21 years of age [+5]

Conditions requiring chronic routine prophylactic use of antibiotics. [+13]

Status: Not yet recruiting

Clinical Outcomes of 3D Printed and Milled Complete Dentures

This is a two-armed, single-center clinical study evaluating performance, efficacy and safety of three dimensional (3D) printed complete dentures and milled complete dentures during a 5-year follow-up period. The primary objective of this clinical investigation is to evaluate survival rate, i.e. subjects with survived dentures in both upper and lower jaw, of 3D printed complete dentures and milled complete dentures after 1 year (in each of the groups separately).

Participants needed: 68
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Dentsply Sirona Implants and ConsumablesUpdated: Jun 8, 2026Locations: 1
Eligibility criteria

Adult aged 18 years or above at time of informed consent. [+6]

Known allergy or hypersensitivity to any of the components. [+13]

Status: Not yet recruiting

Comparasion of Dental Anxiety in First Time Complete Denture Patients

This quasi-experimental study compares dental anxiety levels in edentulous patients at two specific clinical points: the primary impression appointment and the denture insertion appointment. The study aims to determine if the process of receiving first-time complete dentures significantly impacts patient anxiety levels. Data will be collected from 70 participants at the Khyber College of Dentistry over a five-week interval between the two appointments

Participants needed: 70
Trial details
Age: 40-70Biological sex: AllType: InterventionalSponsor: Khyber College of dentistryUpdated: May 19, 2026
Eligibility criteria

Not listed

Status: Recruiting

Changes in Oral Health-related Quality of Life (OHRQoL) During Full Arch Implant Treatment: A Prospective Study

Full arch implant-supported fixed dental prosthesis is widely accepted as a treatment modality for edentulous patients, presenting high long-term implant survival rates, although further research is necessary to evaluate patient satisfaction on a longer term and the psycho-social impact of this treatment on the daily life and functioning of patients. Patient-related outcome measures evaluated through oral health-related quality of life (OHRQol) parameters, patient satisfaction and patient preference allows to evaluate the impact of the prosthodontic needs.

Participants needed: 100
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Implantology InstituteUpdated: May 5, 2026Locations: 2
Eligibility criteria

Systemically good health and absence of contraindications for implant therapy, w...

Status: Recruiting

Occlusion and Dis-Occlusion Time in Mandibular Overdentures Supported by Conventional Versus Mini- Dental Implants

The aim of the study will be comparing between the occlusion and disocclusion time in mandibular single overdenture supported with immediately loaded two conventional implants versus immediately loaded four mini-implants. Research question Is there a difference in occlusion and disocclusion time between two mandibular single dentures, one supported by immediately loaded two conventional implants and the second one supported by immediately loaded four mini-implants? Primary outcome: occlusion and disocclusion time Secondary outcome: Kapur index The null hypothesis is that there is no difference between both treatment modalities on occlusion and disocclusion time.

Participants needed: 28
Trial details
Age: 55-70Biological sex: AllType: InterventionalSponsor: Ain Shams UniversityUpdated: Dec 30, 2025Locations: 2
Eligibility criteria

patients with completely edentulous mandibular ridges and fully dentate or parti... [+2]

The excluded patients will be patients with major systemic diseases that may aff...

Status: Recruiting

Evaluation of Bone Changes Around Implants in Patients Treated With All on Four

The Goal of the clinical trail is to evaluate the Bone height changes around two axially placed anterior implants and two distally inclined 30-degree angle posterior implants in comparison to two axially placed anterior implants and two distally inclined 45-degree angle posterior implants using cone beam CT (CBCT). Patients will visit the clinic after the surgery and after the framework and denture insertion for check ups and during the follow up periods ( at denture insertion, 6 months and 12 months)

Participants needed: 16
Trial details
Age: 50-65Biological sex: AllType: InterventionalSponsor: Al-Azhar UniversityUpdated: Dec 12, 2024Locations: 1
Eligibility criteria

All patients' ages must range from 50-65 years old. [+3]

Patients with oral or systemic diseases. [+5]