Health Trials

EGFR Overexpression

2

Review clinical trials related to EGFR Overexpression. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Clinical Trial of YH32364 in Patients With Locally Advanced or Metastatic EGFR Overexpressing Solid Tumors

This is a study for people with locally advanced or metastatic cancer for whom previous treatment was not successful. Adults aged 18 and over with advanced cancer with Epidermal Growth Factor Receptor (EGFR) overexpressing can join the study. The purpose of this study is to find out whether a medicine called YH32364 helps people with locally advanced or metastatic cancers with EGFR overexpression.

Participants needed: 80
Trial details
Phase: Phase 1, Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Yuhan CorporationUpdated: Jun 10, 2026Locations: 4
Eligibility criteria

Must sign an informed consent form (ICF) prior to any study specific procedures [+12]

Known uncontrolled central nervous system (CNS) metastases, spinal cord compress... [+16]

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Status: Recruiting

HER-2 B Cell Peptide Vaccine

This phase I trial studies the side effects and best dose of vaccine therapy in treating patients with metastatic solid tumors. Vaccines made from antibodies and peptides combined with tumor cells may help the body build an effective immune response to kill tumor cells.

Participants needed: 42
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Pravin T.P KaumayaUpdated: Aug 24, 2025Locations: 1
Eligibility criteria

For the extension cohort to be conducted at the IUSCCC (N=12), patients with his... [+20]

Patients with tumors that are negative for HER-2 expression based on IHC of 0 AN... [+9]

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