Clinical Trial of YH32364 in Patients With Locally Advanced or Metastatic EGFR Overexpressing Solid Tumors

Trial statusRecruiting
Trial phasePhase 1, Phase 2
Trial typeInterventional
Biological sexAll
Age18+
SponsorYuhan Corporation

About this trial

This is a study for people with locally advanced or metastatic cancer for whom previous treatment was not successful. Adults aged 18 and over with advanced cancer with Epidermal Growth Factor Receptor (EGFR) overexpressing can join the study. The purpose of this study is to find out whether a medicine called YH32364 helps people with locally advanced or metastatic cancers with EGFR overexpression.

Eligibility criteria

Qualifiers

Must sign an informed consent form (ICF) prior to any study specific procedures

ECOG performance status 0 or 1

Estimated life expectancy of at least 3 months

A woman must not be breastfeeding

Disqualifiers

Known uncontrolled central nervous system (CNS) metastases, spinal cord compression, and/or carcinomatous meningitis

Have history of a second primary cancer with the exception of

curatively treated non-melanomatous skin cancer

curatively treated cervical or breast carcinoma in situ, or

Trial design

Treatments tested in this trial

  • YH32364

Treatment groups

80 Participants
are divided into 1 treatment group

Sponsors and collaborators