Electronic Nicotine Delivery Systems

Electronic Nicotine Delivery Systems (ENDS) use remains prevalent among young adults, and many have high interest in quitting, yet research on effective intervention is lacking. A mobile health (mHealth) intervention that translates effective smoking cessation materials and pharmacotherapy may be a promising avenue for intervention. The initial phase of the proposed study uses a pilot study to evaluate a novel mHealth intervention for young adult ENDS and dual product (ENDS and combustible cigarette) users.

Goal: Investigate the health effects of electronic cigarettes (e-cigarettes) and whether a short break from using them can improve health. Participants: Up to 148 people (74 who use e-cigarettes and 74 who don't) Age and sex will be matched between the groups. Study Design: Two connected studies: Observational Study: Compares general health (including lung function, heart health, blood pressure, and inflammation) of e-cigarette users to non-smokers. Clinical Trial: E-cigarette users will be randomly assigned to either: Take a 7-day break from e-cigarettes (intervention group) Continue using e-cigarettes as usual (control group) Both groups will have their health measured before and after the 7-day period. Main Outcome: How well your heart and lungs work during exercise. Other Outcomes: Lung function, blood vessel function, risk factors for heart disease, and body measurements. Why is this study important? E-cigarettes are becoming more popular, but their health effects are unknown. This study will provide new information on whether e-cigarettes harm your health and if quitting for a short time can improve it. This information can be used to create better public health policies about e-cigarettes.