Epidural Anesthesia

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Review clinical trials related to Epidural Anesthesia. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Evaluation of the Impact of Ambulatory Epidural on Maternal Satisfaction During Delivery and Postpartum

Childbirth is a special event for women. Maternal satisfaction regarding childbirth is quite important, that is why this factor has to be taken into account. A bad experience related to childbirth could lead to serious psychological and organic consequences such as postpartum depression, mother-baby bond deterioration and chronic pelvic pain. Childbirth image changed over the years to the extent that an increasingly physiological process keeping analgesia and safety is more and more desired. In this perspective, this study aims to investigate an approach so-called ambulatory epidural. Indeed, only a few studies have been conducted and the ones published in 1990s did not involve the current recommended pharmacological protocols.

Participants needed: 126
Trial details
Age: 18+Biological sex: FemaleType: ObservationalSponsor: Centre Hospitalier Régional Metz-ThionvilleUpdated: Jun 24, 2026Locations: 2
Eligibility criteria

Women older than 18 years old [+4]

Hearing or comprehension impairment [+8]

Status: Not yet recruiting

Epidural Catheter Placement Techniques by Anesthesia Residents: Success and Complications

This prospective observational study aims to evaluate the impact of epidural catheter placement techniques - loss of resistance (LOR) and hanging drop (HD) - on first-attempt success rates and procedural complications among anesthesia residents. Residents with at least two years of training will perform epidural catheterization under supervision for patients scheduled for elective surgery requiring perioperative epidural analgesia. An independent observer will record procedural details, complications, and postoperative pain scores. The study will enroll 440 patients aged 18-80 with ASA I-III classification.

Participants needed: 440
Trial details
Age: 18-80Biological sex: AllType: ObservationalSponsor: Marmara University Pendik Training and Research HospitalUpdated: May 7, 2026Locations: 1
Eligibility criteria

Age 18-80 years [+3]

Spinal deformity (scoliosis, kyphosis, or prior spinal surgery at the target lev... [+7]

Status: Recruiting

Nylon Versus Polyurethane Epidural Catheters In Patients Undergoing Major Orthopedic Surgery

Objectives: To compare the safety and efficacy of nylon (polyamide) epidural catheter versus polyurethane epidural catheter in patients undergoing major orthopedic surgery under continuous epidural anesthesia. Background: Continuous epidural anesthesia is the most common anesthetic technique used in orthopedic surgery. However, the use of epidural catheters is associated with complications. The insertion of the catheter may be associated with intravascular or intrathecal placement, nerve root irritation, paresthesia, kinking, hematoma, or breakage during catheter removal. Patients and Methods: This was a prospective, randomized, double-blind clinical trial; carried out on 60 patients undergoing major orthopedic surgery under continuous epidural anesthesia. Patients were randomly allocated into two equal groups; group N, using Nylon catheter, and group P, using Polyurethane catheter.

Participants needed: 60
Trial details
Age: 21-60Biological sex: AllType: InterventionalSponsor: Damanhour Teaching HospitalUpdated: Jan 12, 2026Locations: 1
Eligibility criteria

American Society of Anesthesiologists (ASA) physical status ≤ II [+2]

American Society of Anesthesiologists (ASA) physical status > II [+5]

Status: Not yet recruiting

Erasme Randomized Controlled Trial Surveys Hemodynamic Excursions During Esophagectomy

In our high volume center, the majority of esophagectomy procedures are performed with minimally invasive techniques. The thoracic epidural technique remains the gold standard and homolateral paravertebral catheter is strongly recommended. The vasoplegia and sympathetic blockade due to the epidural can cause significant hypotension especially as reverse Trendelenburg position is required during surgery. The aim is to study hemodynamic changes caused by two different techniques. Previous studies found a similar pain management between both locoregional techniques, however few studies suggested less side effects in the paravertebral group during major abdominal surgeries.

Participants needed: 75
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Erasme University HospitalUpdated: Aug 21, 2024
Eligibility criteria

Adult, Capable of giving consent, two or three incisions esophagectomy (thoracos...

patient refusal, total language barrier, coagulation disorders, thrombocytopenia...