Esketamine and the Quality of Recovery

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Review clinical trials related to Esketamine and the Quality of Recovery. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Clinical Study of Perioperative Sleep Disorders in Cardiac Surgery

The aim of this clinical trial is to understand the effects of dexmedetomidine and esketamine on postoperative sleep in patients undergoing cardiac surgery. The main questions it aims to answer are: Does dexmedetomidine or esketamine prevent the development of postoperative sleep disturbances? Which one works better? The researchers compared dexmedetomidine and esketamine with saline (a drug-free solvent) to see if dexmedetomidine and esketamine prevented the development of postoperative sleep disturbances. Participants will: 1. Intraoperative continuous infusion of dexmedetomidine, esketamine or saline until the end of surgery 2. Postoperative sleep was assessed on the first and third postoperative days using a sleep rating scale

Participants needed: 180
Trial details
Phase: Phase 4Age: 40-75Biological sex: AllType: InterventionalSponsor: Nanjing First Hospital, Nanjing Medical UniversityUpdated: Feb 7, 2025Locations: 2
Eligibility criteria

ASA class II-III, NYHA class I-III, EF ≥ 50% [+1]

Patients undergoing second heart surgery [+6]