Esophageal Stenosis

2

Review clinical trials related to Esophageal Stenosis. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

An Innovative Endoscopic Cap for Dilating Benign Esophageal Strictures in Children

The goal of this study is to find out if using the BougieCap device is a safe and effective way to stretch narrow areas in the esophagus (food pipe) in children. The main questions this study wants to answer are: * Does the BougieCap work well to treat narrow areas in the esophagus comparing with other methods to widen these narrow areas? * Is BougieCap easy to use and does it cause fewer problems or discomfort for children? Researchers will compare two groups: one using the BougieCap, and the other using traditional methods like balloon dilation, to see which one works better and is safer. Participants will: * Answer questions about their symptoms before treatment, 24 hours after, and 14 days later. * Complete these questions during regular hospital visits or over the phone for the final check-up. This study does not involve any extra risks or burdens for the participants.

Participants needed: 40
Trial details
Age: 0-18Biological sex: AllType: InterventionalSponsor: University Children's Hospital, ZurichUpdated: Dec 11, 2024Locations: 3
Eligibility criteria

Age under 18 years of age [+3]

Stenosis that cannot be treated endoscopically [+2]

Status: Not yet recruiting

Esophageal Replacement With a Decellularized Human Esophagus Graft

The aim of the study is to analyze over a 12 month-period, the safety and the efficacy of a circumferentiel oesophageal replacement of the esophagus by a decelularized human esophagus, in 24 patient with a short esophageal stenosis refractory to endoscopic dilatations.

Participants needed: 24
Trial details
Phase: Phase 1, Phase 2Age: 18-65Biological sex: AllType: InterventionalSponsor: Assistance Publique - Hôpitaux de ParisUpdated: Oct 28, 2024
Eligibility criteria

Age: 18 to 65 [+4]

Weight loss > 10% of body weight over last 3 months [+21]