Firearm Injury

9

Review clinical trials related to Firearm Injury. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Recovery Legal Care Clinical Trial

Hospital-Based Violence Intervention Programs (HVIPs) affiliated with trauma centers in the US often focus on individual behavior modification for reduction in re-victimization. There is a lack of reproducible evidence that has demonstrated effectiveness, given the exclusion of addressing inequities in the Social and Structural Determinants of Health (SSDOH), often the root causes of violent injury and preventable homicide. The study investigators created a Medical Legal Partnership (MLP) to partner with an existing HVIP. This novel program offers beside legal assistance to address the SSDOH. The purpose of this study is to evaluate the effectiveness of the HVIP-MLP program in improving perceived stress, violence-related outcomes, legal needs, health-related quality of life, and PTSD symptoms.

Participants needed: 500
Trial details
Age: 14+Biological sex: AllType: InterventionalSponsor: University of ChicagoUpdated: Jun 8, 2026Locations: 1
Eligibility criteria

Treatment for an interpersonal violent injury at the University of Chicago Traum... [+2]

Diagnosis of severe mental illness (e.g., psychotic disorder, schizophrenia, sui... [+7]

Status: Recruiting

Store Safely: Rural Firearm Injury Prevention for Families

The researchers are testing a firearm safety prevention strategy tailored for families with children who reside in a rural area. Researchers hypothesize that the intervention will lead to improvements in household firearm storage.

Participants needed: 600
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of MichiganUpdated: May 14, 2026Locations: 2
Eligibility criteria

Provision of signed and dated informed consent form [+7]

Unable to be consented in English [+7]

Status: Recruiting

BeSMART Secure Storage Counseling in the Inpatient Setting

Firearm injuries are the leading cause of death for American youth. While most of these deaths are homicides, approximately one third are suicides and 5% are unintentional shootings where a child gains access to an unsecured firearm and unintentionally pulls the trigger injuring or killing themselves or someone else. Secure firearm storage in the home has been shown to significantly reduce the risk of both unintentional shootings and intentional self-harm behavior. Additionally, approximately 75% of the guns that show up on school grounds come from the homes of youth or their family members or friends. Despite evidence that secure storage counseling delivered in the pediatric outpatient setting significantly improves secure storage behavior AND recommendations from the American Academy of Pediatrics to provide secure storage counseling during well child checks, rates of counseling continue to be low. The Be SMART program is aligned with the American Academy of Pediatrics policy statement and recommendations and provides a scalable solution to efficient counseling in the clinical setting. However, except for one single site inpatient study, the efficacy of the Be SMART program has not been formally evaluated in the inpatient pediatric setting. By rigorously evaluating the efficacy of specific secure storage interventions like Be SMART the investigators can eventually improve counseling frequency with the goal of increasing gun safety behaviors and reducing firearm injuries and deaths in youth. The investigators hypothesize the Be SMART educational intervention, when delivered in the pediatric inpatient setting, will lead to significant improvement in the primary gun safety behavior endpoint and the secondary endpoint among both gun owners and non-gun owners when compared to control group.

Participants needed: 400
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Vanderbilt University Medical CenterUpdated: May 11, 2026Locations: 2
Eligibility criteria

Provision of signed and dated informed consent form [+3]

Caregivers of children admitted for firearm injury [+3]

Status: Not yet recruiting

Trial of a Nurse-Led Firearm Safety Intervention in the Pediatric Inpatient Setting

In this randomized controlled trial, researchers will assess the effectiveness and implementation of S.A.F.E. Firearm in the inpatient pediatric hospital setting. S.A.F.E. Firearm has been adapted for nurse-led delivery to parents/caregivers (hereafter, parents) of hospitalized youth. Adapted S.A.F.E. Firearm involves a brief discussion between nurses and parents about secure firearm storage and an offer of a free firearm cable lock. Researchers will test S.A.F.E. Firearm and a bundle of strategies intended to support the routinization of S.A.F.E. Firearm into nursing workflows. The questions the study aims to answer are: * How effective is adapted S.A.F.E. Firearm at changing parents' firearm storage behavior? * How effective is the implementation strategy bundle at increasing delivery of adapted S.A.F.E. Firearm? Some parents will be invited to participate in surveys about their experiences with adapted S.A.F.E. Firearm, and some nurses will be invited to participate in interviews about their experiences with the implementation strategy bundle.

Participants needed: 7,200
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of PennsylvaniaUpdated: Apr 13, 2026Locations: 2
Eligibility criteria

Nurses who work on a nursing unit randomized to the intervention arm

Not a nurse who works on a nursing unit randomized to the intervention arm [+7]

Status: Recruiting

HVIP Outcomes and Stakeholder Insights

The study's goal is to perform an evaluation of a Southeastern hospital violence intervention program (HVIP) that includes comprehensive patient outcomes, perceived benefits and opportunities for improvement of an HVIP from the perspectives of multiple stakeholders including patients, family members and healthcare providers.

Participants needed: 220
Trial details
Age: 16+Biological sex: AllType: InterventionalSponsor: Medical University of South CarolinaUpdated: Apr 9, 2026Locations: 1
Eligibility criteria

Patients ages 16 and above treated at MUSC Charleston that experience an injury... [+1]

Lack of capacity to consent due to altered mental status (AMS) or severe untreat... [+6]

Status: Recruiting

TRUsted rEsidents and Housing Assistance to Decrease Violence Exposure in New Haven

The overall objective of this study is to implement and test a strengths-based, community-driven intervention to reduce gun violence by (1) improving housing stability through providing financial assistance coupled with comprehensive financial education for the re-entry population as well as their family members, and (2) fostering greater support for mental health by training a trusted network of community members in trauma-informed counseling.

Participants needed: 61,770
Trial details
Biological sex: AllType: InterventionalSponsor: Yale UniversityUpdated: Feb 13, 2026Locations: 7
Eligibility criteria

Age 18 or above [+3]

Status: Recruiting

Launching the Houston Hospital-Based Violence Intervention Program (Houston-HVIP): Developing and Evaluating a Hospital-Based Intervention to Reduce Recurrent Violence

A prior violent injury is one of the strongest predictors of future violent injury, highlighting the importance of effective hospital-based interventions to prevent reinjury. This project will establish and evaluate the Houston Hospital-Based Violence Intervention Program (Houston-HVIP). Using a randomized controlled trial, the study will assess the effectiveness of Houston-HVIP in reducing violent reinjury and improving behavioral, mental, and physical health outcomes over a 12-month follow-up period among those enrolled in the study in ages 16-35 years of age.

Participants needed: 274
Trial details
Age: 16-35Biological sex: AllType: InterventionalSponsor: The University of Texas Health Science Center, HoustonUpdated: Jan 21, 2026Locations: 1
Eligibility criteria

presented for a gunshot injury stemming from community violence at Memorial Herm... [+3]

presenting for a firearm injury arising from a self-inflicted gunshot or uninten... [+1]

Status: Recruiting

Addressing Root Causes for Gun Violence Prevention (ARC-GVP)

The goal of this study is to help build the evidence base for a locally-relevant youth firearm violence prevention program in Washington D.C., a city experiencing disparities in youth firearm violence outcomes. The main question it aims to answer is: How is youth participation in the summer youth employment program, the True Reasons I Grabbed the Gun Evolved from Risk (The T.R.I.G.G.E.R Project), which is designed to address root causes of gun violence, associated with individual youth behavioral outcomes, including pro-social involvement, aggression, and firearm-related attitudes and behaviors?

Participants needed: 250
Trial details
Age: 14-24Biological sex: AllType: ObservationalSponsor: University of MichiganUpdated: Aug 14, 2025Locations: 1
Eligibility criteria

Youth in Washington D.C. who are participating in The T.R.I.G.G.E.R Project, a g...

Emancipated minors

Status: Recruiting

Project Safe Guard-Trauma

The goal of this randomized controlled trial is to determine if a counseling intervention, Project Safe Guard-Trauma (PSG-T), increases secure firearm storage practices in adults who screen positive for posttraumatic stress disorder (PTSD). The main questions this study aims to answer are: * Does PSG-T lead to more secure firearm storage practices? * Does PSG-T increase knowledge about the link between firearm storage practices and suicide risk? * Does PSG-T increase intentions to store firearms securely? Researchers will compare PSG-T to a control, Project Safe Guard (PSG), which is a counseling intervention that does not focus on the potential influence of PTSD symptoms on firearm storage practices. This will help to determine if PSG-T works better than PSG to increase secure firearm storage in adults with elevated PTSD symptoms. Participants will: * Complete a baseline survey * Receive the counseling intervention * Complete a survey immediately after the intervention and at 1-, 3-, and 6-months following the intervention

Participants needed: 168
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University of Colorado, DenverUpdated: May 20, 2025Locations: 1
Eligibility criteria

Aged 18+ years [+6]

Currently stores all personal firearms unloaded and locked [+3]