Status: Recruiting
FMISO-based Adaptive Radiotherapy for Head and Neck Cancer
Hypoxia occurs in about 80% of head and neck tumors. Based on experimental and clinical data, hypoxia is a useful parameter for pretherapeutic stratification. These radioresistant regions can be detected with FMISO PET/CT. Moreover, hypoxic subvolumes of tumors can be evolving as target volumes for radiotherapy ("dose painting") in hypoxia imaging-based dose escalation.
Participants needed: 120
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: University Hospital OlomoucUpdated: Apr 22, 2025Locations: 3
Eligibility criteria
Pathologically proven new diagnosis of oropharyngeal p16 negative, or laryngeal,... [+4]
Prior surgical treatment - any surgery of primary tumor or involved nodes or pri... [+8]