Hemorrhoidal Bleeding

2

Review clinical trials related to Hemorrhoidal Bleeding. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Prospective HemorrhoIdaL EmboliSation (PILES) Registry

The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of hemorrhoid artery embolization (HAE) for symptomatic bleeding internal hemorrhoids in adults aged 18 years or older that have not responded to medical therapy. The main question it aims to answer are: 1\) Does HAE lead to sustained improvement in bleeding (HDSS scores over 12-36 months? Participants will: * Undergo HAE as part of their routine clinical care. * Complete clinical follow-up assessments at 1, 3, 6, 12, 18, 24, and 36 months after treatment, including symptom and quality-of-life questionnaires. * Have safety outcomes tracked according to Society of Interventional Radiology guidelines. There is no comparison group; results will be analyzed to identify predictors of success and inform best practices for patient selection and treatment.

Participants needed: 1,200
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Joint & Vascular InstituteUpdated: Jun 12, 2026Locations: 1Duration: 5 Years
Eligibility criteria

Adults (≥18 years) with symptomatic bleeding internal hemorrhoids refractory to...

Pregnancy, coagulopathy, severe comorbidities, or inability to consent.

Status: Recruiting

Rectal Arterial Embolization vs Band Ligation for the Treatment of Internal hemOrrhoidS

The purpose of this clinical trial is to compare two standard of care non-surgical treatments for hemorrhoidal bleeding: hemorrhoidal artery embolization (HAE) versus rubber band ligation (RBL). Directly comparing these two methods may help to clarify which treatment is better for controlling hemorrhoidal bleeding, reducing symptoms, and improving patients' quality of life. HAE is a standard minimally invasive procedure to put tiny particles or coils into the blood vessel that feeds a hemorrhoid to block the blood flow (embolization). This involves using a catheter inserted into an artery, using twilight (conscious) sedation. RBL is a standard procedure that involves using small rubber bands around the base of the hemorrhoids to cut off blood flow, causing it to shrink or shrivel.

Participants needed: 40
Trial details
Age: 18-89Biological sex: AllType: InterventionalSponsor: Jessica K. Stewart, MDUpdated: May 8, 2026Locations: 1
Eligibility criteria

Age ≥ 18 years and less than 90 years. [+5]

Moderate loss of kidney function, defined as estimated glomerular filtration rat... [+9]