Health Trials

Inborn Errors of Immunity

2

Review clinical trials related to Inborn Errors of Immunity. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Immunodysregulation As an Expression of Underlying Inborn Errors of Immunity: Implementation of Diagnostics and Management of Pediatric and Adult Patients with Immune System Disorders

This is an observational, retro-prospective, moncentric study focused on Inborn Errors of Immunity, an heterogeneous group of inherited diseases due to defects in the differentiation and/or function of the immune system. The primary aim of this study is to obtain a clinical-immunological, functional and molecular characterisation of paediatric and adult patients with confirmed or suspected Inborn Errors of Immunity, particularly of patients with manifestations of immunedysregulation, focusing on clinical course, immunophenotypic laboratory and functional abnormalities, genetic background.

Participants needed: 400
Trial details
Age: Up to 50Biological sex: AllType: ObservationalSponsor: IRCCS Azienda Ospedaliero-Universitaria di BolognaUpdated: Jan 14, 2025Locations: 1
Eligibility criteria

patients with confirmed or suspected Inborn Errors of Immunity; [+2]

Read more
Status: Recruiting

PTCy and and Ruxolitinib for GVHD Prophylaxis After HSCT With Thymoglobulin in Conditioning Regimen in Patients With Inborn Errors of Immunity

The aim of the current study is to evaluate the efficacy of combined regimen of GVHD prophylaxis with thymoglobulin in conditioning regimen and PTCY with ruxolitinib used after HSCT in patients with inborn errors of immunity (IEI)

Participants needed: 100
Trial details
Phase: Phase 2Age: 0-21Biological sex: AllType: InterventionalSponsor: Federal Research Institute of Pediatric Hematology, Oncology and ImmunologyUpdated: Jan 10, 2024Locations: 1
Eligibility criteria

Patients aged ≥ 0 months and < 21 years [+2]

Read more